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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LPP All Species: 19.39
Human Site: Y346 Identified Species: 35.56
UniProt: Q93052 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q93052 NP_005569.1 612 65746 Y346 N Q N P P G M Y P V T G P K K
Chimpanzee Pan troglodytes XP_001159584 680 73450 Y414 N Q N P P G M Y P V T G P K K
Rhesus Macaque Macaca mulatta XP_001104284 416 44041 V159 S P P V S T P V T G H K R M V
Dog Lupus familis XP_850342 615 65837 Y349 N Q N P A G M Y P V A G P K K
Cat Felis silvestris
Mouse Mus musculus Q8BFW7 613 65872 Y347 N Q N H P G M Y P V S G P K K
Rat Rattus norvegicus Q5XI07 632 68242 Y343 N Q N Q P G M Y S V S G P K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512190 613 66056 Y347 P Q N P A G M Y Q P P G T K K
Chicken Gallus gallus Q5F464 604 65121 P338 N T V G Q A P P G M Y Q H P G
Frog Xenopus laevis A5H447 663 70707 K398 S T G G K D M K P L P E G L R
Zebra Danio Brachydanio rerio A8DZE6 648 70883 L369 H L Q T F P V L E E P Q Q Q N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396072 477 52619 I220 Y E S I Y E P I N P R P P S Q
Nematode Worm Caenorhab. elegans Q09476 413 46434 I155 P L H S D S M I G T M N G E L
Sea Urchin Strong. purpuratus XP_798292 448 48550 G191 Q Q T S P T P G P S P A P K P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.8 66.5 92.5 N.A. 89.4 83.8 N.A. 81.4 78.7 31.8 27 N.A. N.A. 34.6 22 38.2
Protein Similarity: 100 89.8 66.8 93.9 N.A. 92 87.8 N.A. 84 82.6 45.8 41.6 N.A. N.A. 49.8 35.2 46.9
P-Site Identity: 100 100 0 86.6 N.A. 86.6 80 N.A. 60 6.6 13.3 0 N.A. N.A. 6.6 6.6 33.3
P-Site Similarity: 100 100 6.6 86.6 N.A. 93.3 86.6 N.A. 60 13.3 33.3 20 N.A. N.A. 26.6 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 16 8 0 0 0 0 8 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 8 0 0 8 8 0 8 0 8 0 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 16 0 47 0 8 16 8 0 47 16 0 8 % G
% His: 8 0 8 8 0 0 0 0 0 0 8 0 8 0 0 % H
% Ile: 0 0 0 8 0 0 0 16 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 0 0 8 0 0 0 8 0 54 47 % K
% Leu: 0 16 0 0 0 0 0 8 0 8 0 0 0 8 8 % L
% Met: 0 0 0 0 0 0 62 0 0 8 8 0 0 8 0 % M
% Asn: 47 0 47 0 0 0 0 0 8 0 0 8 0 0 8 % N
% Pro: 16 8 8 31 39 8 31 8 47 16 31 8 54 8 8 % P
% Gln: 8 54 8 8 8 0 0 0 8 0 0 16 8 8 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 8 % R
% Ser: 16 0 8 16 8 8 0 0 8 8 16 0 0 8 0 % S
% Thr: 0 16 8 8 0 16 0 0 8 8 16 0 8 0 0 % T
% Val: 0 0 8 8 0 0 8 8 0 39 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 8 0 0 47 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _