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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LPP All Species: 30.3
Human Site: Y469 Identified Species: 55.56
UniProt: Q93052 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q93052 NP_005569.1 612 65746 Y469 K A Y C E P C Y I N T L E Q C
Chimpanzee Pan troglodytes XP_001159584 680 73450 Y537 K A Y C E P C Y I N T L E Q C
Rhesus Macaque Macaca mulatta XP_001104284 416 44041 G281 Y A Y I P P P G L Q P E P G Y
Dog Lupus familis XP_850342 615 65837 Y472 K A Y C E P C Y I N T L E Q C
Cat Felis silvestris
Mouse Mus musculus Q8BFW7 613 65872 Y470 K A Y C E P C Y I N T L E Q C
Rat Rattus norvegicus Q5XI07 632 68242 Y489 K A Y C E P C Y I N T L E Q C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512190 613 66056 Y470 K A Y C E P C Y I N T L E Q C
Chicken Gallus gallus Q5F464 604 65121 Y461 K A Y C E P C Y I N T L E Q C
Frog Xenopus laevis A5H447 663 70707 Y525 K P L C D E C Y Q D T L E C C
Zebra Danio Brachydanio rerio A8DZE6 648 70883 F497 E D F L Y S G F Q Q T A E K C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396072 477 52619 V342 N T L E K C C V C T R P I L D
Nematode Worm Caenorhab. elegans Q09476 413 46434 N277 E D G F H E K N G Q T Y C K R
Sea Urchin Strong. purpuratus XP_798292 448 48550 N313 F C E H C Y V N S L E K C S T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.8 66.5 92.5 N.A. 89.4 83.8 N.A. 81.4 78.7 31.8 27 N.A. N.A. 34.6 22 38.2
Protein Similarity: 100 89.8 66.8 93.9 N.A. 92 87.8 N.A. 84 82.6 45.8 41.6 N.A. N.A. 49.8 35.2 46.9
P-Site Identity: 100 100 20 100 N.A. 100 100 N.A. 100 100 53.3 20 N.A. N.A. 6.6 6.6 0
P-Site Similarity: 100 100 26.6 100 N.A. 100 100 N.A. 100 100 66.6 46.6 N.A. N.A. 13.3 20 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 62 0 0 0 0 0 0 0 0 0 8 0 0 0 % A
% Cys: 0 8 0 62 8 8 70 0 8 0 0 0 16 8 70 % C
% Asp: 0 16 0 0 8 0 0 0 0 8 0 0 0 0 8 % D
% Glu: 16 0 8 8 54 16 0 0 0 0 8 8 70 0 0 % E
% Phe: 8 0 8 8 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 0 8 8 8 0 0 0 0 8 0 % G
% His: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 54 0 0 0 8 0 0 % I
% Lys: 62 0 0 0 8 0 8 0 0 0 0 8 0 16 0 % K
% Leu: 0 0 16 8 0 0 0 0 8 8 0 62 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 16 0 54 0 0 0 0 0 % N
% Pro: 0 8 0 0 8 62 8 0 0 0 8 8 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 16 24 0 0 0 54 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % R
% Ser: 0 0 0 0 0 8 0 0 8 0 0 0 0 8 0 % S
% Thr: 0 8 0 0 0 0 0 0 0 8 77 0 0 0 8 % T
% Val: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 62 0 8 8 0 62 0 0 0 8 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _