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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP2A3
All Species:
14.55
Human Site:
Y497
Identified Species:
29.09
UniProt:
Q93084
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93084
NP_005164.2
1043
113977
Y497
D
R
K
S
M
S
V
Y
C
T
P
T
R
P
H
Chimpanzee
Pan troglodytes
XP_001141455
997
109629
K481
V
I
K
Q
L
M
K
K
E
F
T
L
E
F
S
Rhesus Macaque
Macaca mulatta
XP_001092550
998
108889
K481
V
I
K
Q
L
M
Q
K
E
F
T
L
E
F
S
Dog
Lupus familis
XP_548558
1008
110281
F489
R
K
E
F
T
L
E
F
S
R
D
R
K
S
M
Cat
Felis silvestris
Mouse
Mus musculus
Q64518
1038
113590
Y497
D
R
K
S
M
S
V
Y
C
T
P
T
R
A
D
Rat
Rattus norvegicus
P18596
999
109341
E482
I
K
Q
L
M
Q
K
E
F
T
L
E
F
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9YGL9
1042
115411
Y497
D
R
K
S
M
S
V
Y
C
T
P
T
G
P
G
Frog
Xenopus laevis
NP_001088563
1033
114381
Y497
D
R
K
S
M
S
V
Y
C
N
S
E
A
P
N
Zebra Danio
Brachydanio rerio
XP_697108
970
107056
F452
Q
K
K
F
T
L
E
F
S
R
D
R
K
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22700
1020
111683
Y497
D
R
K
S
M
S
S
Y
C
T
P
L
K
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SY55
998
109042
K483
Y
W
E
N
Q
F
K
K
V
Y
V
L
E
F
T
Baker's Yeast
Sacchar. cerevisiae
P13586
950
104552
G429
V
R
E
T
L
T
I
G
N
L
C
N
N
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
93.1
90.1
N.A.
93.2
90.5
N.A.
N.A.
78.9
77.9
73.5
N.A.
65
N.A.
N.A.
N.A.
Protein Similarity:
100
84.2
94.4
92.2
N.A.
95.4
93
N.A.
N.A.
88.4
88
83.6
N.A.
77.2
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
0
N.A.
86.6
13.3
N.A.
N.A.
86.6
66.6
6.6
N.A.
66.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
13.3
26.6
N.A.
86.6
26.6
N.A.
N.A.
86.6
73.3
26.6
N.A.
73.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
53.3
31.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
67.7
51.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
9
25
0
% A
% Cys:
0
0
0
0
0
0
0
0
42
0
9
0
0
0
0
% C
% Asp:
42
0
0
0
0
0
0
0
0
0
17
0
0
0
9
% D
% Glu:
0
0
25
0
0
0
17
9
17
0
0
17
25
0
0
% E
% Phe:
0
0
0
17
0
9
0
17
9
17
0
0
9
25
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
9
17
0
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
25
67
0
0
0
25
25
0
0
0
0
25
0
0
% K
% Leu:
0
0
0
9
25
17
0
0
0
9
9
34
0
0
0
% L
% Met:
0
0
0
0
50
17
0
0
0
0
0
0
0
0
17
% M
% Asn:
0
0
0
9
0
0
0
0
9
9
0
9
9
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
34
0
0
25
0
% P
% Gln:
9
0
9
17
9
9
9
0
0
0
0
0
0
0
0
% Q
% Arg:
9
50
0
0
0
0
0
0
0
17
0
17
17
0
9
% R
% Ser:
0
0
0
42
0
42
9
0
17
0
9
0
0
25
34
% S
% Thr:
0
0
0
9
17
9
0
0
0
42
17
25
0
0
9
% T
% Val:
25
0
0
0
0
0
34
0
9
0
9
0
0
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
42
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _