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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
P2RX5
All Species:
13.64
Human Site:
Y21
Identified Species:
33.33
UniProt:
Q93086
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93086
NP_002552.2
422
47205
Y21
F
D
Y
K
T
E
K
Y
V
I
A
K
N
K
K
Chimpanzee
Pan troglodytes
XP_511272
422
47228
Y21
F
D
Y
K
T
E
K
Y
V
I
A
K
N
K
K
Rhesus Macaque
Macaca mulatta
XP_001117644
375
41862
Dog
Lupus familis
XP_548343
428
47818
Y21
F
D
Y
K
T
E
K
Y
V
I
A
K
N
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJX6
388
43419
R19
L
F
E
Y
D
T
P
R
I
V
L
I
R
S
R
Rat
Rattus norvegicus
P51578
455
51461
F21
F
D
Y
K
T
A
K
F
V
V
A
K
S
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508992
486
53195
G95
P
A
G
D
R
A
E
G
S
R
P
D
R
A
P
Chicken
Gallus gallus
NP_990079
402
45138
Y21
F
D
Y
K
T
E
K
Y
V
I
A
K
N
K
K
Frog
Xenopus laevis
NP_001082067
391
44317
R21
L
F
D
Y
D
T
P
R
I
A
L
I
K
S
R
Zebra Danio
Brachydanio rerio
NP_919394
481
54639
F20
L
D
Y
K
T
E
K
F
V
I
A
K
N
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
73.6
67
N.A.
44
63.5
N.A.
46.9
59.2
43.5
46.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
77.4
77
N.A.
61.1
75.1
N.A.
61.3
72.7
60.9
60.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
0
73.3
N.A.
0
100
0
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
0
100
N.A.
20
93.3
N.A.
6.6
100
13.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
20
0
0
0
10
60
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
60
10
10
20
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
10
0
0
50
10
0
0
0
0
0
0
0
0
% E
% Phe:
50
20
0
0
0
0
0
20
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
20
50
0
20
0
0
0
% I
% Lys:
0
0
0
60
0
0
60
0
0
0
0
60
10
60
60
% K
% Leu:
30
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% N
% Pro:
10
0
0
0
0
0
20
0
0
0
10
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
20
0
10
0
0
20
0
20
% R
% Ser:
0
0
0
0
0
0
0
0
10
0
0
0
10
20
0
% S
% Thr:
0
0
0
0
60
20
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
60
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
60
20
0
0
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _