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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BHMT All Species: 37.27
Human Site: T339 Identified Species: 82
UniProt: Q93088 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q93088 NP_001704.2 406 44998 T339 G S G L D M H T K P W V R A R
Chimpanzee Pan troglodytes XP_517686 554 61013 T487 G S G L D M H T K P W V R A R
Rhesus Macaque Macaca mulatta XP_001104072 544 60332 T477 G S G L D M H T K P W V R A R
Dog Lupus familis XP_536313 407 45084 T339 G S G L D M H T K P W I R A R
Cat Felis silvestris
Mouse Mus musculus O35490 407 45002 T339 G S G L D M H T K P W I R A R
Rat Rattus norvegicus O09171 407 44958 T339 G S G L D M H T K P W I R A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517846 419 46578 T350 G S G L D M H T K P W I R A R
Chicken Gallus gallus XP_414685 405 44992 S336 K H G S W G N S L S M H T K P
Frog Xenopus laevis Q5XGM3 403 44162 T336 G S G L E M H T K P W V R A R
Zebra Danio Brachydanio rerio Q32LQ4 400 44048 T334 G S G L E M H T K P W V R A R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781040 408 44889 Q342 L W G D G L R Q H T K P W V R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72.7 70.4 94.8 N.A. 94.3 92.3 N.A. 86.4 85.2 83.9 77.3 N.A. N.A. N.A. N.A. 63.2
Protein Similarity: 100 72.9 71.8 97.7 N.A. 97.3 96 N.A. 91.4 92.6 90.6 87.6 N.A. N.A. N.A. N.A. 77.9
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 93.3 6.6 93.3 93.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 20 100 100 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 82 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 64 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 82 0 100 0 10 10 0 0 0 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 82 0 10 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 37 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 82 0 10 0 0 10 0 % K
% Leu: 10 0 0 82 0 10 0 0 10 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 82 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 82 0 10 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 0 0 0 0 82 0 91 % R
% Ser: 0 82 0 10 0 0 0 10 0 10 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 82 0 10 0 0 10 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 46 0 10 0 % V
% Trp: 0 10 0 0 10 0 0 0 0 0 82 0 10 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _