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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BHMT
All Species:
43.33
Human Site:
Y284
Identified Species:
95.33
UniProt:
Q93088
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93088
NP_001704.2
406
44998
Y284
T
R
W
D
I
Q
K
Y
A
R
E
A
Y
N
L
Chimpanzee
Pan troglodytes
XP_517686
554
61013
Y432
T
R
W
D
I
Q
K
Y
A
R
E
A
Y
N
L
Rhesus Macaque
Macaca mulatta
XP_001104072
544
60332
Y422
T
R
W
D
I
Q
K
Y
A
R
E
A
Y
N
L
Dog
Lupus familis
XP_536313
407
45084
Y284
T
R
W
D
I
Q
K
Y
A
R
E
A
Y
N
L
Cat
Felis silvestris
Mouse
Mus musculus
O35490
407
45002
Y284
T
R
W
D
I
Q
K
Y
A
R
E
A
Y
N
L
Rat
Rattus norvegicus
O09171
407
44958
Y284
T
R
W
D
I
Q
K
Y
A
R
E
A
Y
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517846
419
46578
Y295
T
R
W
D
I
Q
K
Y
A
R
E
A
Y
E
L
Chicken
Gallus gallus
XP_414685
405
44992
Y286
T
R
W
D
V
Q
K
Y
A
R
K
A
Y
D
L
Frog
Xenopus laevis
Q5XGM3
403
44162
Y281
T
R
W
D
I
H
K
Y
A
R
A
A
Y
D
L
Zebra Danio
Brachydanio rerio
Q32LQ4
400
44048
Y279
T
R
W
E
M
Q
Q
Y
A
R
E
A
Y
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781040
408
44889
Y289
T
R
W
E
C
H
R
Y
A
R
E
A
Y
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.7
70.4
94.8
N.A.
94.3
92.3
N.A.
86.4
85.2
83.9
77.3
N.A.
N.A.
N.A.
N.A.
63.2
Protein Similarity:
100
72.9
71.8
97.7
N.A.
97.3
96
N.A.
91.4
92.6
90.6
87.6
N.A.
N.A.
N.A.
N.A.
77.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
80
80
66.6
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
86.6
86.6
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
100
0
10
100
0
0
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
82
0
0
0
0
0
0
0
0
0
28
0
% D
% Glu:
0
0
0
19
0
0
0
0
0
0
82
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
73
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
82
0
0
0
10
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
82
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
55
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
82
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
100
0
0
0
0
10
0
0
100
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
100
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _