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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HGD
All Species:
22.73
Human Site:
T395
Identified Species:
41.67
UniProt:
Q93099
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93099
NP_000178.2
445
49964
T395
P
E
R
I
A
D
G
T
M
A
F
M
F
E
S
Chimpanzee
Pan troglodytes
XP_516674
445
49898
T395
P
E
R
I
A
D
G
T
M
A
F
M
F
E
S
Rhesus Macaque
Macaca mulatta
XP_001110996
445
49894
T395
P
E
R
I
A
D
G
T
M
A
F
M
F
E
S
Dog
Lupus familis
XP_535754
442
49512
T392
P
E
R
I
A
D
G
T
M
A
F
M
F
E
S
Cat
Felis silvestris
Mouse
Mus musculus
O09173
445
49971
T395
P
E
R
I
A
D
G
T
M
A
F
M
F
E
S
Rat
Rattus norvegicus
NP_001012145
445
49881
T395
P
E
R
I
A
D
G
T
M
A
F
M
F
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416553
439
49447
P388
A
S
K
A
K
L
E
P
E
R
V
A
E
G
T
Frog
Xenopus laevis
NP_001087504
443
50048
P388
A
R
K
A
K
L
E
P
E
R
V
A
E
G
T
Zebra Danio
Brachydanio rerio
NP_694498
443
49866
G394
K
P
E
R
V
A
E
G
T
M
A
F
M
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKJ0
439
49379
R390
N
A
K
L
V
P
E
R
V
A
E
G
T
Q
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9Y041
437
49220
K388
M
A
S
N
A
D
L
K
P
Q
R
V
A
E
G
Sea Urchin
Strong. purpuratus
XP_001189424
555
61925
I503
A
P
L
K
A
E
R
I
A
D
G
T
M
A
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZRA2
461
51437
G401
M
A
P
S
K
L
T
G
T
M
A
F
M
F
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.4
93.7
N.A.
92.3
91
N.A.
N.A.
82.4
80
79.5
N.A.
65.8
N.A.
64.7
54.9
Protein Similarity:
100
99.3
99.5
97
N.A.
96.8
96.1
N.A.
N.A.
91
88.7
88.3
N.A.
78.1
N.A.
77.7
65
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
0
0
0
N.A.
6.6
N.A.
20
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
13.3
0
N.A.
40
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
24
0
16
62
8
0
0
8
54
16
16
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
54
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
47
8
0
0
8
31
0
16
0
8
0
16
54
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
47
16
47
16
8
% F
% Gly:
0
0
0
0
0
0
47
16
0
0
8
8
0
16
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
47
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
8
0
24
8
24
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
8
0
24
8
0
0
0
0
0
0
0
0
% L
% Met:
16
0
0
0
0
0
0
0
47
16
0
47
24
0
0
% M
% Asn:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
47
16
8
0
0
8
0
16
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% Q
% Arg:
0
8
47
8
0
0
8
8
0
16
8
0
0
0
0
% R
% Ser:
0
8
8
8
0
0
0
0
0
0
0
0
0
0
47
% S
% Thr:
0
0
0
0
0
0
8
47
16
0
0
8
8
0
16
% T
% Val:
0
0
0
0
16
0
0
0
8
0
16
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _