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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LEAP2
All Species:
15.03
Human Site:
S73
Identified Species:
47.25
UniProt:
Q969E1
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969E1
NP_443203.1
77
8814
S73
R
K
R
R
C
S
L
S
V
A
Q
E
_
_
_
Chimpanzee
Pan troglodytes
XP_001164030
81
9272
P73
R
K
G
Q
Q
S
P
P
T
M
L
R
S
M
E
Rhesus Macaque
Macaca mulatta
Q95M25
77
8783
S73
R
K
R
R
C
S
L
S
V
A
Q
E
_
_
_
Dog
Lupus familis
XP_852172
77
8932
S73
R
K
R
R
C
S
L
S
V
A
Q
E
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q91V13
76
8518
S72
R
K
R
R
C
S
L
S
V
A
Q
E
_
_
_
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511514
65
7254
E59
A
S
C
R
D
N
S
E
C
I
T
L
L
C
_
Chicken
Gallus gallus
NP_001001606
76
8817
R72
R
K
N
R
C
F
L
R
T
A
S
E
_
_
_
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001122249
92
10194
S87
R
M
G
H
C
S
Y
S
Q
P
V
N
S
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
98.6
89.6
N.A.
84.4
N.A.
N.A.
53.2
57.1
N.A.
38
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90.1
98.6
93.5
N.A.
89.6
N.A.
N.A.
63.6
68.8
N.A.
53.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
100
100
N.A.
100
N.A.
N.A.
7.1
58.3
N.A.
30.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
N.A.
N.A.
14.2
58.3
N.A.
30.7
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
0
0
0
0
0
63
0
0
0
0
0
% A
% Cys:
0
0
13
0
75
0
0
0
13
0
0
0
0
13
0
% C
% Asp:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
13
0
0
0
63
0
0
13
% E
% Phe:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% I
% Lys:
0
75
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
63
0
0
0
13
13
13
0
0
% L
% Met:
0
13
0
0
0
0
0
0
0
13
0
0
0
13
0
% M
% Asn:
0
0
13
0
0
13
0
0
0
0
0
13
0
0
0
% N
% Pro:
0
0
0
0
0
0
13
13
0
13
0
0
0
0
0
% P
% Gln:
0
0
0
13
13
0
0
0
13
0
50
0
0
0
0
% Q
% Arg:
88
0
50
75
0
0
0
13
0
0
0
13
0
0
0
% R
% Ser:
0
13
0
0
0
75
13
63
0
0
13
0
25
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
25
0
13
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
50
0
13
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
63
75
88
% _