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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TSR2 All Species: 10
Human Site: T129 Identified Species: 22
UniProt: Q969E8 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969E8 NP_477511.1 191 20894 T129 V T A T A L K T A R E T D E D
Chimpanzee Pan troglodytes XP_001151586 59 6221
Rhesus Macaque Macaca mulatta XP_001090023 191 20891 T129 V T A T A L K T A K E T D E D
Dog Lupus familis XP_538053 189 20622 V127 Y R V R A T A V A T A R E T D
Cat Felis silvestris
Mouse Mus musculus Q8C8T8 191 20873 T129 V T A T P L M T A K E T D V A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510102 177 19404 I112 G A T L Q E M I T Q M A Q K S
Chicken Gallus gallus
Frog Xenopus laevis Q3KPN2 189 20559 V126 K Y D V R A K V Q E V T P S D
Zebra Danio Brachydanio rerio Q3KRG3 181 19973 K119 I L K L N Q K K T S S G R A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797024 200 21510 G136 N M Q A M L G G M R L G Q Q S
Poplar Tree Populus trichocarpa XP_002328370 213 23506 S148 H V K Q A V D S D D D S E D S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06672 205 23695 K138 L Y L E W Q E K Q R T K K S K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 30.3 98.4 87.4 N.A. 85.8 N.A. N.A. 56.5 N.A. 44.5 46 N.A. N.A. N.A. N.A. 33.5
Protein Similarity: 100 30.8 98.9 92.1 N.A. 91 N.A. N.A. 67.5 N.A. 60.7 61.2 N.A. N.A. N.A. N.A. 51.5
P-Site Identity: 100 0 93.3 20 N.A. 66.6 N.A. N.A. 0 N.A. 20 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 0 100 26.6 N.A. 73.3 N.A. N.A. 13.3 N.A. 20 13.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 25.3 N.A. N.A. N.A. 26.8 N.A.
Protein Similarity: 46.4 N.A. N.A. N.A. 44.8 N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 46.6 N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 28 10 37 10 10 0 37 0 10 10 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 10 0 10 10 10 0 28 10 37 % D
% Glu: 0 0 0 10 0 10 10 0 0 10 28 0 19 19 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 10 10 0 0 0 19 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 10 0 19 0 0 0 37 19 0 19 0 10 10 10 19 % K
% Leu: 10 10 10 19 0 37 0 0 0 0 10 0 0 0 0 % L
% Met: 0 10 0 0 10 0 19 0 10 0 10 0 0 0 0 % M
% Asn: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % P
% Gln: 0 0 10 10 10 19 0 0 19 10 0 0 19 10 0 % Q
% Arg: 0 10 0 10 10 0 0 0 0 28 0 10 10 0 0 % R
% Ser: 0 0 0 0 0 0 0 10 0 10 10 10 0 19 28 % S
% Thr: 0 28 10 28 0 10 0 28 19 10 10 37 0 10 0 % T
% Val: 28 10 10 10 0 10 0 19 0 0 10 0 0 10 0 % V
% Trp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _