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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSR2
All Species:
12.42
Human Site:
T133
Identified Species:
27.33
UniProt:
Q969E8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969E8
NP_477511.1
191
20894
T133
A
L
K
T
A
R
E
T
D
E
D
E
D
D
V
Chimpanzee
Pan troglodytes
XP_001151586
59
6221
Rhesus Macaque
Macaca mulatta
XP_001090023
191
20891
T133
A
L
K
T
A
K
E
T
D
E
D
E
D
D
V
Dog
Lupus familis
XP_538053
189
20622
R131
A
T
A
V
A
T
A
R
E
T
D
E
D
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8C8T8
191
20873
T133
P
L
M
T
A
K
E
T
D
V
A
E
D
D
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510102
177
19404
A116
Q
E
M
I
T
Q
M
A
Q
K
S
Q
V
K
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Q3KPN2
189
20559
T130
R
A
K
V
Q
E
V
T
P
S
D
D
E
E
E
Zebra Danio
Brachydanio rerio
Q3KRG3
181
19973
G123
N
Q
K
K
T
S
S
G
R
A
K
A
T
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797024
200
21510
G140
M
L
G
G
M
R
L
G
Q
Q
S
H
G
S
S
Poplar Tree
Populus trichocarpa
XP_002328370
213
23506
S152
A
V
D
S
D
D
D
S
E
D
S
G
N
D
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06672
205
23695
K142
W
Q
E
K
Q
R
T
K
K
S
K
R
V
V
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.3
98.4
87.4
N.A.
85.8
N.A.
N.A.
56.5
N.A.
44.5
46
N.A.
N.A.
N.A.
N.A.
33.5
Protein Similarity:
100
30.8
98.9
92.1
N.A.
91
N.A.
N.A.
67.5
N.A.
60.7
61.2
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
0
93.3
46.6
N.A.
66.6
N.A.
N.A.
0
N.A.
20
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
0
100
53.3
N.A.
73.3
N.A.
N.A.
20
N.A.
40
6.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
25.3
N.A.
N.A.
N.A.
26.8
N.A.
Protein Similarity:
46.4
N.A.
N.A.
N.A.
44.8
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
60
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
10
10
0
37
0
10
10
0
10
10
10
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
10
10
0
28
10
37
10
37
46
10
% D
% Glu:
0
10
10
0
0
10
28
0
19
19
0
37
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
10
0
0
0
19
0
0
0
10
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
37
19
0
19
0
10
10
10
19
0
0
10
0
% K
% Leu:
0
37
0
0
0
0
10
0
0
0
0
0
0
0
0
% L
% Met:
10
0
19
0
10
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% P
% Gln:
10
19
0
0
19
10
0
0
19
10
0
10
0
0
0
% Q
% Arg:
10
0
0
0
0
28
0
10
10
0
0
10
0
0
0
% R
% Ser:
0
0
0
10
0
10
10
10
0
19
28
0
0
10
10
% S
% Thr:
0
10
0
28
19
10
10
37
0
10
0
0
10
0
0
% T
% Val:
0
10
0
19
0
0
10
0
0
10
0
0
19
10
37
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _