KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSR2
All Species:
16.06
Human Site:
T173
Identified Species:
35.33
UniProt:
Q969E8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969E8
NP_477511.1
191
20894
T173
P
S
D
P
D
A
Q
T
I
K
E
E
D
I
V
Chimpanzee
Pan troglodytes
XP_001151586
59
6221
K42
G
G
V
H
S
Q
E
K
A
K
W
L
G
G
A
Rhesus Macaque
Macaca mulatta
XP_001090023
191
20891
T173
P
S
D
P
D
A
Q
T
I
K
E
E
D
I
V
Dog
Lupus familis
XP_538053
189
20622
T171
S
S
G
P
D
S
Q
T
I
K
E
E
D
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8C8T8
191
20873
T173
P
S
D
P
D
T
Q
T
I
K
E
E
D
I
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510102
177
19404
L156
T
S
L
A
L
S
G
L
L
R
G
T
V
E
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Q3KPN2
189
20559
P170
A
L
G
P
S
S
A
P
K
K
E
E
E
P
E
Zebra Danio
Brachydanio rerio
Q3KRG3
181
19973
D163
V
S
S
T
A
V
N
D
L
H
H
E
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797024
200
21510
S180
S
S
S
S
S
I
N
S
R
Q
E
P
A
E
D
Poplar Tree
Populus trichocarpa
XP_002328370
213
23506
K192
P
V
N
V
P
R
A
K
E
A
Q
S
E
D
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06672
205
23695
S182
E
V
V
P
D
L
V
S
S
K
P
E
P
I
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.3
98.4
87.4
N.A.
85.8
N.A.
N.A.
56.5
N.A.
44.5
46
N.A.
N.A.
N.A.
N.A.
33.5
Protein Similarity:
100
30.8
98.9
92.1
N.A.
91
N.A.
N.A.
67.5
N.A.
60.7
61.2
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
6.6
100
80
N.A.
93.3
N.A.
N.A.
6.6
N.A.
26.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
100
86.6
N.A.
93.3
N.A.
N.A.
26.6
N.A.
40
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
25.3
N.A.
N.A.
N.A.
26.8
N.A.
Protein Similarity:
46.4
N.A.
N.A.
N.A.
44.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
10
19
19
0
10
10
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
28
0
46
0
0
10
0
0
0
0
37
10
10
% D
% Glu:
10
0
0
0
0
0
10
0
10
0
55
64
28
28
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
19
0
0
0
10
0
0
0
10
0
10
10
19
% G
% His:
0
0
0
10
0
0
0
0
0
10
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
37
0
0
0
0
46
0
% I
% Lys:
0
0
0
0
0
0
0
19
10
64
0
0
0
0
0
% K
% Leu:
0
10
10
0
10
10
0
10
19
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
19
0
0
0
0
0
0
0
0
% N
% Pro:
37
0
0
55
10
0
0
10
0
0
10
10
10
10
0
% P
% Gln:
0
0
0
0
0
10
37
0
0
10
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
10
10
0
0
0
0
0
% R
% Ser:
19
64
19
10
28
28
0
19
10
0
0
10
0
0
0
% S
% Thr:
10
0
0
10
0
10
0
37
0
0
0
10
0
0
0
% T
% Val:
10
19
19
10
0
10
10
0
0
0
0
0
10
0
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _