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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKD2
All Species:
35.45
Human Site:
S146
Identified Species:
86.67
UniProt:
Q969F2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969F2
NP_149111.1
451
50055
S146
V
T
R
E
D
M
S
S
L
M
H
T
I
Y
E
Chimpanzee
Pan troglodytes
XP_517607
438
48518
S132
V
T
R
E
D
M
S
S
L
M
H
T
I
Y
E
Rhesus Macaque
Macaca mulatta
XP_001096345
454
50531
S146
V
T
R
E
D
M
S
S
L
M
H
T
I
Y
E
Dog
Lupus familis
XP_545194
600
65102
S296
A
T
R
E
D
M
S
S
L
M
H
T
I
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE28
461
51483
S154
V
T
R
E
D
M
S
S
L
M
H
T
I
Y
E
Rat
Rattus norvegicus
NP_001100924
458
51317
S149
V
T
R
E
D
M
S
S
L
M
H
T
I
Y
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506035
574
63910
S270
V
T
K
E
D
M
S
S
L
M
H
T
I
Y
E
Chicken
Gallus gallus
XP_414094
469
52712
S164
V
T
R
E
D
I
T
S
L
L
H
T
I
Y
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4ZNR5
409
47117
V93
G
E
R
D
A
Q
K
V
K
K
R
I
S
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795739
590
65888
S163
I
T
R
E
D
L
S
S
I
L
K
S
I
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.8
94.9
53.5
N.A.
76.7
77
N.A.
51.2
45.2
N.A.
47.6
N.A.
N.A.
N.A.
N.A.
21.1
Protein Similarity:
100
91.1
95.8
60.6
N.A.
82.4
82.7
N.A.
59.7
59
N.A.
62.5
N.A.
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
93.3
80
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
100
100
N.A.
20
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
90
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
90
0
0
0
0
0
0
0
0
0
0
90
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
80
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
0
10
0
0
10
90
0
0
% I
% Lys:
0
0
10
0
0
0
10
0
10
10
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
80
20
0
0
0
10
0
% L
% Met:
0
0
0
0
0
70
0
0
0
70
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
90
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
80
90
0
0
0
10
10
10
0
% S
% Thr:
0
90
0
0
0
0
10
0
0
0
0
80
0
0
0
% T
% Val:
70
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
80
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _