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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NKD2 All Species: 26.36
Human Site: S180 Identified Species: 64.44
UniProt: Q969F2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969F2 NP_149111.1 451 50055 S180 L T V S P E P S S K R K E G P
Chimpanzee Pan troglodytes XP_517607 438 48518 S166 L T V S P E P S S K R K E G P
Rhesus Macaque Macaca mulatta XP_001096345 454 50531 S180 L T V S P E P S S K R K E G P
Dog Lupus familis XP_545194 600 65102 Y330 L T V S P E S Y G G R K D S P
Cat Felis silvestris
Mouse Mus musculus Q8VE28 461 51483 S188 L T V S P E P S S K K E C P L
Rat Rattus norvegicus NP_001100924 458 51317 S183 L T V S P E P S S K K E W L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506035 574 63910 S304 L T V S P E P S G K R K G G L
Chicken Gallus gallus XP_414094 469 52712 S198 L T V A P D G S Q K K K S I L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A4ZNR5 409 47117 G127 L Y D F D N S G K V T K E D M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795739 590 65888 E197 L S M L S D H E R D T R K K T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.8 94.9 53.5 N.A. 76.7 77 N.A. 51.2 45.2 N.A. 47.6 N.A. N.A. N.A. N.A. 21.1
Protein Similarity: 100 91.1 95.8 60.6 N.A. 82.4 82.7 N.A. 59.7 59 N.A. 62.5 N.A. N.A. N.A. N.A. 37.2
P-Site Identity: 100 100 100 60 N.A. 66.6 73.3 N.A. 80 46.6 N.A. 20 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 66.6 N.A. 80 86.6 N.A. 80 66.6 N.A. 20 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 10 0 10 20 0 0 0 10 0 0 10 10 0 % D
% Glu: 0 0 0 0 0 70 0 10 0 0 0 20 40 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 10 20 10 0 0 10 40 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 10 70 30 70 10 10 0 % K
% Leu: 100 0 0 10 0 0 0 0 0 0 0 0 0 10 30 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 80 0 60 0 0 0 0 0 0 10 50 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 0 50 10 0 0 0 % R
% Ser: 0 10 0 70 10 0 20 70 50 0 0 0 10 10 0 % S
% Thr: 0 80 0 0 0 0 0 0 0 0 20 0 0 0 10 % T
% Val: 0 0 80 0 0 0 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _