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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKD2
All Species:
12.73
Human Site:
S23
Identified Species:
31.11
UniProt:
Q969F2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969F2
NP_149111.1
451
50055
S23
R
E
S
P
E
G
D
S
F
V
A
S
A
Y
A
Chimpanzee
Pan troglodytes
XP_517607
438
48518
A31
R
G
S
V
S
P
L
A
F
R
E
L
P
N
G
Rhesus Macaque
Macaca mulatta
XP_001096345
454
50531
S23
R
E
S
P
E
G
D
S
F
V
A
S
A
Y
A
Dog
Lupus familis
XP_545194
600
65102
P26
R
G
H
R
W
E
Q
P
Q
S
S
S
V
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE28
461
51483
S23
R
E
S
P
E
G
D
S
F
V
V
P
A
Y
G
Rat
Rattus norvegicus
NP_001100924
458
51317
V23
P
E
G
D
S
F
V
V
S
A
Y
A
S
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506035
574
63910
T142
I
Q
D
G
L
R
E
T
K
R
N
A
F
R
A
Chicken
Gallus gallus
XP_414094
469
52712
F23
E
S
P
E
G
D
S
F
A
V
N
A
S
L
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4ZNR5
409
47117
V23
P
E
G
D
S
F
V
V
N
G
F
I
A
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795739
590
65888
S26
R
E
N
P
E
G
D
S
Y
I
L
R
G
C
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.8
94.9
53.5
N.A.
76.7
77
N.A.
51.2
45.2
N.A.
47.6
N.A.
N.A.
N.A.
N.A.
21.1
Protein Similarity:
100
91.1
95.8
60.6
N.A.
82.4
82.7
N.A.
59.7
59
N.A.
62.5
N.A.
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
20
100
13.3
N.A.
80
6.6
N.A.
6.6
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
26.6
100
20
N.A.
80
20
N.A.
33.3
26.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
10
10
20
30
40
0
40
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
10
20
0
10
40
0
0
0
0
0
0
0
0
% D
% Glu:
10
60
0
10
40
10
10
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
20
0
10
40
0
10
0
10
0
0
% F
% Gly:
0
20
20
10
10
40
0
0
0
10
0
0
10
10
20
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
10
0
10
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% K
% Leu:
0
0
0
0
10
0
10
0
0
0
10
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
10
0
20
0
0
10
0
% N
% Pro:
20
0
10
40
0
10
0
10
0
0
0
10
10
0
0
% P
% Gln:
0
10
0
0
0
0
10
0
10
0
0
0
0
0
0
% Q
% Arg:
60
0
0
10
0
10
0
0
0
20
0
10
0
10
20
% R
% Ser:
0
10
40
0
30
0
10
40
10
10
10
30
20
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
20
20
0
40
10
0
10
10
10
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
10
0
0
30
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _