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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKD2
All Species:
25.15
Human Site:
S299
Identified Species:
61.48
UniProt:
Q969F2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969F2
NP_149111.1
451
50055
S299
H
A
V
H
H
R
R
S
Q
V
L
V
E
H
V
Chimpanzee
Pan troglodytes
XP_517607
438
48518
S285
H
A
V
H
H
R
R
S
Q
V
L
V
E
H
V
Rhesus Macaque
Macaca mulatta
XP_001096345
454
50531
S299
H
A
V
H
H
R
R
S
Q
V
L
V
E
H
V
Dog
Lupus familis
XP_545194
600
65102
S449
H
S
A
W
H
R
R
S
Q
V
L
A
D
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE28
461
51483
S306
H
A
I
H
H
R
R
S
Q
V
L
A
E
H
V
Rat
Rattus norvegicus
NP_001100924
458
51317
S301
H
A
I
H
H
R
R
S
Q
V
L
A
E
H
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506035
574
63910
S423
H
P
G
H
H
R
R
S
Q
V
L
A
E
Y
P
Chicken
Gallus gallus
XP_414094
469
52712
Q315
H
A
H
H
R
K
S
Q
V
V
D
P
S
H
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4ZNR5
409
47117
S244
A
G
I
E
N
Y
T
S
R
F
D
S
S
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795739
590
65888
A318
P
E
R
H
H
R
K
A
R
K
S
S
A
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.8
94.9
53.5
N.A.
76.7
77
N.A.
51.2
45.2
N.A.
47.6
N.A.
N.A.
N.A.
N.A.
21.1
Protein Similarity:
100
91.1
95.8
60.6
N.A.
82.4
82.7
N.A.
59.7
59
N.A.
62.5
N.A.
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
100
100
53.3
N.A.
86.6
80
N.A.
66.6
33.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
66.6
N.A.
93.3
93.3
N.A.
73.3
46.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
60
10
0
0
0
0
10
0
0
0
40
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
20
0
10
0
0
% D
% Glu:
0
10
0
10
0
0
0
0
0
0
0
0
60
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
10
10
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
80
0
10
80
80
0
0
0
0
0
0
0
0
60
0
% H
% Ile:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
20
% I
% Lys:
0
0
0
0
0
10
10
0
0
10
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
70
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
0
0
0
0
0
0
0
0
0
10
0
10
30
% P
% Gln:
0
0
0
0
0
0
0
10
70
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
10
80
70
0
20
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
0
0
10
80
0
0
10
20
20
10
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% T
% Val:
0
0
30
0
0
0
0
0
10
80
0
30
0
0
50
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _