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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKD2
All Species:
19.09
Human Site:
S394
Identified Species:
46.67
UniProt:
Q969F2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969F2
NP_149111.1
451
50055
S394
Q
K
G
R
E
G
H
S
P
L
K
A
P
H
A
Chimpanzee
Pan troglodytes
XP_517607
438
48518
S380
Q
K
G
R
E
G
H
S
P
P
K
A
P
H
A
Rhesus Macaque
Macaca mulatta
XP_001096345
454
50531
S397
Q
K
G
R
E
G
H
S
P
L
K
A
P
H
A
Dog
Lupus familis
XP_545194
600
65102
S543
Q
R
S
R
E
G
H
S
P
L
K
A
A
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE28
461
51483
H404
R
Q
K
A
R
E
G
H
S
P
L
K
G
H
G
Rat
Rattus norvegicus
NP_001100924
458
51317
H399
R
Q
K
S
R
E
G
H
S
P
L
K
G
H
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506035
574
63910
S517
Q
K
A
K
D
A
H
S
P
L
R
A
T
H
A
Chicken
Gallus gallus
XP_414094
469
52712
Q414
Q
R
A
K
E
N
H
Q
M
C
K
T
F
Q
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4ZNR5
409
47117
T352
Q
N
H
T
H
A
H
T
P
S
G
L
Q
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795739
590
65888
T531
R
R
S
R
R
H
H
T
L
Q
P
L
T
V
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.8
94.9
53.5
N.A.
76.7
77
N.A.
51.2
45.2
N.A.
47.6
N.A.
N.A.
N.A.
N.A.
21.1
Protein Similarity:
100
91.1
95.8
60.6
N.A.
82.4
82.7
N.A.
59.7
59
N.A.
62.5
N.A.
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
93.3
100
66.6
N.A.
6.6
6.6
N.A.
60
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
100
73.3
N.A.
20
20
N.A.
80
46.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
10
0
20
0
0
0
0
0
50
10
0
40
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
50
20
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
30
0
0
40
20
0
0
0
10
0
20
0
30
% G
% His:
0
0
10
0
10
10
80
20
0
0
0
0
0
70
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
40
20
20
0
0
0
0
0
0
50
20
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
10
40
20
20
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% M
% Asn:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
60
30
10
0
30
0
0
% P
% Gln:
70
20
0
0
0
0
0
10
0
10
0
0
10
10
0
% Q
% Arg:
30
30
0
50
30
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
20
10
0
0
0
50
20
10
0
0
0
0
20
% S
% Thr:
0
0
0
10
0
0
0
20
0
0
0
10
20
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _