KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX4
All Species:
13.64
Human Site:
S289
Identified Species:
27.27
UniProt:
Q969G2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969G2
NP_203129.1
390
43124
S289
G
G
Q
L
M
N
G
S
F
S
M
D
G
T
G
Chimpanzee
Pan troglodytes
Q5IS44
406
44776
A305
Q
G
P
P
S
S
Q
A
Q
T
P
V
D
L
P
Rhesus Macaque
Macaca mulatta
XP_001115069
390
43011
S289
G
G
Q
L
M
N
G
S
F
S
M
D
G
T
G
Dog
Lupus familis
XP_547420
390
43059
S289
G
G
Q
L
M
N
G
S
F
S
M
D
G
T
G
Cat
Felis silvestris
Mouse
Mus musculus
P53776
390
43059
S289
G
G
Q
L
M
N
G
S
F
S
M
D
G
T
G
Rat
Rattus norvegicus
P61376
402
44369
F295
A
P
G
G
N
Y
D
F
F
A
H
G
P
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P53412
395
43787
D294
T
N
G
G
F
S
L
D
H
S
G
I
P
A
Q
Frog
Xenopus laevis
P36200
395
44013
E294
S
N
G
P
F
S
L
E
H
G
G
I
P
T
Q
Zebra Danio
Brachydanio rerio
Q90421
398
44208
G286
P
A
L
S
R
Q
G
G
N
H
P
A
F
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRC7
275
31013
D177
D
S
N
P
D
G
Q
D
L
E
R
I
A
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20271
351
40037
A252
R
W
K
S
S
N
R
A
E
S
D
S
N
S
P
Sea Urchin
Strong. purpuratus
XP_780701
485
54161
P352
N
D
R
H
H
H
G
P
P
G
I
P
L
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.3
98.9
99.2
N.A.
98.9
27.8
N.A.
N.A.
68.8
67.5
63.3
N.A.
24.3
N.A.
41.2
42.6
Protein Similarity:
100
46.7
98.9
99.2
N.A.
99.2
46
N.A.
N.A.
80.5
79.7
76.6
N.A.
39.7
N.A.
56.4
56.2
P-Site Identity:
100
6.6
100
100
N.A.
100
6.6
N.A.
N.A.
6.6
6.6
6.6
N.A.
0
N.A.
13.3
6.6
P-Site Similarity:
100
26.6
100
100
N.A.
100
13.3
N.A.
N.A.
13.3
13.3
6.6
N.A.
6.6
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
0
0
17
0
9
0
9
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
0
9
0
9
17
0
0
9
34
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
9
9
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
17
0
0
9
42
0
0
0
9
0
0
% F
% Gly:
34
42
25
17
0
9
50
9
0
17
17
9
34
0
34
% G
% His:
0
0
0
9
9
9
0
0
17
9
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
25
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
34
0
0
17
0
9
0
0
0
9
9
9
% L
% Met:
0
0
0
0
34
0
0
0
0
0
34
0
0
0
0
% M
% Asn:
9
17
9
0
9
42
0
0
9
0
0
0
9
0
0
% N
% Pro:
9
9
9
25
0
0
0
9
9
0
17
9
25
17
17
% P
% Gln:
9
0
34
0
0
9
17
0
9
0
0
0
0
0
17
% Q
% Arg:
9
0
9
0
9
0
9
0
0
0
9
0
0
0
0
% R
% Ser:
9
9
0
17
17
25
0
34
0
50
0
9
0
25
17
% S
% Thr:
9
0
0
0
0
0
0
0
0
9
0
0
0
42
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _