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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LHX4 All Species: 15.45
Human Site: S318 Identified Species: 30.91
UniProt: Q969G2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969G2 NP_203129.1 390 43124 S318 P Q S P S S I S S L P S H A P
Chimpanzee Pan troglodytes Q5IS44 406 44776 H334 L E H P L P G H H P S S E A Q
Rhesus Macaque Macaca mulatta XP_001115069 390 43011 S318 P Q S P S S I S S L P S H A P
Dog Lupus familis XP_547420 390 43059 S318 P Q S P S S I S S L P S H A P
Cat Felis silvestris
Mouse Mus musculus P53776 390 43059 S318 P Q S P S S I S S L P S H A P
Rat Rattus norvegicus P61376 402 44369 G324 G P G S T P L G A L E P P L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P53412 395 43787 Q323 P Q S P A S L Q A L P G H Q P
Frog Xenopus laevis P36200 395 44013 Q323 P Q S P A S L Q S M P G H Q S
Zebra Danio Brachydanio rerio Q90421 398 44208 S315 I Q A S S P Y S L P Q S P G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IRC7 275 31013 H206 S R A R Q K K H I H A G K N K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P20271 351 40037 N281 D H P M D D G N E S N Y L F H
Sea Urchin Strong. purpuratus XP_780701 485 54161 G381 T A P S V N S G Y P V N N P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27.3 98.9 99.2 N.A. 98.9 27.8 N.A. N.A. 68.8 67.5 63.3 N.A. 24.3 N.A. 41.2 42.6
Protein Similarity: 100 46.7 98.9 99.2 N.A. 99.2 46 N.A. N.A. 80.5 79.7 76.6 N.A. 39.7 N.A. 56.4 56.2
P-Site Identity: 100 20 100 100 N.A. 100 6.6 N.A. N.A. 60 53.3 33.3 N.A. 0 N.A. 0 0
P-Site Similarity: 100 26.6 100 100 N.A. 100 26.6 N.A. N.A. 80 73.3 40 N.A. 13.3 N.A. 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 17 0 17 0 0 0 17 0 9 0 0 42 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 0 0 0 0 0 0 9 0 9 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 9 0 9 0 0 0 17 17 0 0 0 25 0 9 0 % G
% His: 0 9 9 0 0 0 0 17 9 9 0 0 50 0 9 % H
% Ile: 9 0 0 0 0 0 34 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 9 9 0 0 0 0 0 9 0 9 % K
% Leu: 9 0 0 0 9 0 25 0 9 50 0 0 9 9 0 % L
% Met: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 9 0 0 9 9 9 9 0 % N
% Pro: 50 9 17 59 0 25 0 0 0 25 50 9 17 9 50 % P
% Gln: 0 59 0 0 9 0 0 17 0 0 9 0 0 17 9 % Q
% Arg: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 0 50 25 42 50 9 42 42 9 9 50 0 0 17 % S
% Thr: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 9 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _