KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX4
All Species:
17.88
Human Site:
S319
Identified Species:
35.76
UniProt:
Q969G2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969G2
NP_203129.1
390
43124
S319
Q
S
P
S
S
I
S
S
L
P
S
H
A
P
L
Chimpanzee
Pan troglodytes
Q5IS44
406
44776
H335
E
H
P
L
P
G
H
H
P
S
S
E
A
Q
R
Rhesus Macaque
Macaca mulatta
XP_001115069
390
43011
S319
Q
S
P
S
S
I
S
S
L
P
S
H
A
P
L
Dog
Lupus familis
XP_547420
390
43059
S319
Q
S
P
S
S
I
S
S
L
P
S
H
A
P
L
Cat
Felis silvestris
Mouse
Mus musculus
P53776
390
43059
S319
Q
S
P
S
S
I
S
S
L
P
S
H
A
P
L
Rat
Rattus norvegicus
P61376
402
44369
A325
P
G
S
T
P
L
G
A
L
E
P
P
L
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P53412
395
43787
A324
Q
S
P
A
S
L
Q
A
L
P
G
H
Q
P
L
Frog
Xenopus laevis
P36200
395
44013
S324
Q
S
P
A
S
L
Q
S
M
P
G
H
Q
S
L
Zebra Danio
Brachydanio rerio
Q90421
398
44208
L316
Q
A
S
S
P
Y
S
L
P
Q
S
P
G
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRC7
275
31013
I207
R
A
R
Q
K
K
H
I
H
A
G
K
N
K
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20271
351
40037
E282
H
P
M
D
D
G
N
E
S
N
Y
L
F
H
S
Sea Urchin
Strong. purpuratus
XP_780701
485
54161
Y382
A
P
S
V
N
S
G
Y
P
V
N
N
P
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.3
98.9
99.2
N.A.
98.9
27.8
N.A.
N.A.
68.8
67.5
63.3
N.A.
24.3
N.A.
41.2
42.6
Protein Similarity:
100
46.7
98.9
99.2
N.A.
99.2
46
N.A.
N.A.
80.5
79.7
76.6
N.A.
39.7
N.A.
56.4
56.2
P-Site Identity:
100
20
100
100
N.A.
100
6.6
N.A.
N.A.
60
53.3
40
N.A.
0
N.A.
0
0
P-Site Similarity:
100
26.6
100
100
N.A.
100
26.6
N.A.
N.A.
80
73.3
46.6
N.A.
20
N.A.
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
0
17
0
0
0
17
0
9
0
0
42
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
9
0
9
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
9
0
0
0
17
17
0
0
0
25
0
9
0
9
% G
% His:
9
9
0
0
0
0
17
9
9
0
0
50
0
9
0
% H
% Ile:
0
0
0
0
0
34
0
9
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
0
9
9
0
0
0
0
0
9
0
9
0
% K
% Leu:
0
0
0
9
0
25
0
9
50
0
0
9
9
0
59
% L
% Met:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
9
0
0
9
9
9
9
0
0
% N
% Pro:
9
17
59
0
25
0
0
0
25
50
9
17
9
50
9
% P
% Gln:
59
0
0
9
0
0
17
0
0
9
0
0
17
9
0
% Q
% Arg:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
50
25
42
50
9
42
42
9
9
50
0
0
17
9
% S
% Thr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
9
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _