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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX4
All Species:
14.24
Human Site:
Y228
Identified Species:
28.48
UniProt:
Q969G2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969G2
NP_203129.1
390
43124
Y228
R
H
R
W
G
Q
F
Y
K
S
V
K
R
S
R
Chimpanzee
Pan troglodytes
Q5IS44
406
44776
L244
R
M
K
Q
L
S
A
L
G
A
R
R
H
A
F
Rhesus Macaque
Macaca mulatta
XP_001115069
390
43011
Y228
R
H
R
W
G
Q
F
Y
K
S
V
K
R
S
R
Dog
Lupus familis
XP_547420
390
43059
Y228
R
H
R
W
G
Q
F
Y
K
S
V
K
R
S
R
Cat
Felis silvestris
Mouse
Mus musculus
P53776
390
43059
Y228
R
H
R
W
G
Q
F
Y
K
S
V
K
R
S
R
Rat
Rattus norvegicus
P61376
402
44369
K234
W
F
Q
N
R
R
S
K
E
R
R
M
K
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P53412
395
43787
G233
R
N
M
K
R
S
R
G
T
S
K
S
D
K
D
Frog
Xenopus laevis
P36200
395
44013
G233
R
N
M
K
R
S
R
G
N
S
K
S
D
K
D
Zebra Danio
Brachydanio rerio
Q90421
398
44208
F225
R
Q
R
W
G
Q
Y
F
R
N
M
K
R
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRC7
275
31013
R116
Q
F
A
L
M
D
D
R
V
L
C
K
A
H
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20271
351
40037
S191
R
T
T
I
S
A
K
S
L
E
T
L
K
Q
A
Sea Urchin
Strong. purpuratus
XP_780701
485
54161
R291
H
Y
F
R
N
I
K
R
V
N
E
A
S
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.3
98.9
99.2
N.A.
98.9
27.8
N.A.
N.A.
68.8
67.5
63.3
N.A.
24.3
N.A.
41.2
42.6
Protein Similarity:
100
46.7
98.9
99.2
N.A.
99.2
46
N.A.
N.A.
80.5
79.7
76.6
N.A.
39.7
N.A.
56.4
56.2
P-Site Identity:
100
6.6
100
100
N.A.
100
0
N.A.
N.A.
13.3
13.3
60
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
33.3
100
100
N.A.
100
26.6
N.A.
N.A.
20
20
93.3
N.A.
13.3
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
9
0
0
9
0
9
9
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
9
0
0
0
0
0
17
0
17
% D
% Glu:
0
0
0
0
0
0
0
0
9
9
9
0
0
0
0
% E
% Phe:
0
17
9
0
0
0
34
9
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
42
0
0
17
9
0
0
0
0
0
0
% G
% His:
9
34
0
0
0
0
0
0
0
0
0
0
9
9
0
% H
% Ile:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
17
0
0
17
9
34
0
17
50
17
17
0
% K
% Leu:
0
0
0
9
9
0
0
9
9
9
0
9
0
0
9
% L
% Met:
0
9
17
0
9
0
0
0
0
0
9
9
0
0
0
% M
% Asn:
0
17
0
9
9
0
0
0
9
17
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
9
9
9
9
0
42
0
0
0
0
0
0
0
17
0
% Q
% Arg:
75
0
42
9
25
9
17
17
9
9
17
9
42
0
42
% R
% Ser:
0
0
0
0
9
25
9
9
0
50
0
17
9
50
0
% S
% Thr:
0
9
9
0
0
0
0
0
9
0
9
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
17
0
34
0
0
0
0
% V
% Trp:
9
0
0
42
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
9
34
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _