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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX4
All Species:
16.97
Human Site:
Y274
Identified Species:
33.94
UniProt:
Q969G2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969G2
NP_203129.1
390
43124
Y274
L
G
H
T
N
R
I
Y
G
N
V
G
D
V
T
Chimpanzee
Pan troglodytes
Q5IS44
406
44776
G290
Q
S
E
Y
Y
G
P
G
G
N
Y
D
F
F
P
Rhesus Macaque
Macaca mulatta
XP_001115069
390
43011
Y274
L
G
H
T
N
R
I
Y
G
N
V
G
D
V
T
Dog
Lupus familis
XP_547420
390
43059
Y274
L
G
H
T
N
R
I
Y
G
N
V
G
D
V
T
Cat
Felis silvestris
Mouse
Mus musculus
P53776
390
43059
Y274
L
G
H
T
N
R
I
Y
G
N
V
G
D
V
T
Rat
Rattus norvegicus
P61376
402
44369
G280
S
T
P
Y
T
Y
Y
G
D
Y
Q
S
D
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P53412
395
43787
P279
S
N
L
S
E
A
S
P
A
L
G
R
Q
A
G
Frog
Xenopus laevis
P36200
395
44013
P279
N
S
L
N
D
S
S
P
V
L
G
R
Q
A
G
Zebra Danio
Brachydanio rerio
Q90421
398
44208
Y271
L
G
H
S
N
G
I
Y
S
S
L
S
E
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRC7
275
31013
V162
F
T
E
E
Q
L
Q
V
L
Q
A
N
F
Q
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20271
351
40037
R237
N
R
R
A
K
E
K
R
L
K
K
D
A
G
R
Sea Urchin
Strong. purpuratus
XP_780701
485
54161
P337
D
D
H
S
P
G
M
P
D
H
G
I
T
F
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.3
98.9
99.2
N.A.
98.9
27.8
N.A.
N.A.
68.8
67.5
63.3
N.A.
24.3
N.A.
41.2
42.6
Protein Similarity:
100
46.7
98.9
99.2
N.A.
99.2
46
N.A.
N.A.
80.5
79.7
76.6
N.A.
39.7
N.A.
56.4
56.2
P-Site Identity:
100
13.3
100
100
N.A.
100
6.6
N.A.
N.A.
0
0
40
N.A.
0
N.A.
0
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
6.6
N.A.
N.A.
6.6
6.6
73.3
N.A.
0
N.A.
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
9
0
0
9
0
9
0
9
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
0
9
0
0
0
17
0
0
17
42
0
0
% D
% Glu:
0
0
17
9
9
9
0
0
0
0
0
0
9
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
17
17
0
% F
% Gly:
0
42
0
0
0
25
0
17
42
0
25
34
0
9
17
% G
% His:
0
0
50
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
42
0
0
0
0
9
0
0
9
% I
% Lys:
0
0
0
0
9
0
9
0
0
9
9
0
0
0
0
% K
% Leu:
42
0
17
0
0
9
0
0
17
17
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
17
9
0
9
42
0
0
0
0
42
0
9
0
0
0
% N
% Pro:
0
0
9
0
9
0
9
25
0
0
0
0
0
0
9
% P
% Gln:
9
0
0
0
9
0
9
0
0
9
9
0
17
9
9
% Q
% Arg:
0
9
9
0
0
34
0
9
0
0
0
17
0
0
9
% R
% Ser:
17
17
0
25
0
9
17
0
9
9
0
17
0
9
9
% S
% Thr:
0
17
0
34
9
0
0
0
0
0
0
0
9
0
34
% T
% Val:
0
0
0
0
0
0
0
9
9
0
34
0
0
34
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
17
9
9
9
42
0
9
9
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _