Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RFK All Species: 43.03
Human Site: S111 Identified Species: 72.82
UniProt: Q969G6 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969G6 NP_060809.2 155 17623 S111 R P E K N F D S L E S L I S A
Chimpanzee Pan troglodytes XP_001149206 186 20421 S142 R P E K N F D S L E S L I S A
Rhesus Macaque Macaca mulatta XP_001092264 116 12991 V88 E I L N V A I V D Y L R P E K
Dog Lupus familis XP_541275 589 64931 S545 R P E K N F D S L E S L I S A
Cat Felis silvestris
Mouse Mus musculus Q8CFV9 155 17418 S111 R P E K N F D S L E S L I S A
Rat Rattus norvegicus NP_001014128 155 17462 S111 R P E K N F D S L E S L I S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516422 191 21780 S111 R P E E S F E S I D A L I A A
Chicken Gallus gallus NP_001026776 155 17559 S111 R P E K N F D S L D A L I A A
Frog Xenopus laevis NP_001079669 172 19314 S129 R P E K S F T S L D A L I S A
Zebra Danio Brachydanio rerio XP_689407 163 18463 S111 R P E R G F T S L D E L I T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76206 153 16967 S112 R P E R S F D S L E S L I A A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789693 130 14954 I102 I A A I K E D I A D A D M K L
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001146905 398 43718 S344 R P E A N F P S L E S L I E R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q6M923 210 23418 G163 R N E K D Y S G L E A L I A D
Conservation
Percent
Protein Identity: 100 73.1 70.3 25.1 N.A. 93.5 93.5 N.A. 57 78.7 65.6 73 N.A. 58.7 N.A. N.A. 53.5
Protein Similarity: 100 74.7 72.9 25.9 N.A. 98 98.7 N.A. 73.8 92.9 76.7 84.6 N.A. 76.1 N.A. N.A. 65.8
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 53.3 80 73.3 60 N.A. 80 N.A. N.A. 6.6
P-Site Similarity: 100 100 0 100 N.A. 100 100 N.A. 100 100 93.3 80 N.A. 100 N.A. N.A. 26.6
Percent
Protein Identity: N.A. 22.3 N.A. N.A. N.A. 31.9
Protein Similarity: N.A. 29.9 N.A. N.A. N.A. 46.6
P-Site Identity: N.A. 73.3 N.A. N.A. N.A. 46.6
P-Site Similarity: N.A. 73.3 N.A. N.A. N.A. 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 8 0 8 0 0 8 0 36 0 0 29 72 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 58 0 8 36 0 8 0 0 8 % D
% Glu: 8 0 86 8 0 8 8 0 0 58 8 0 0 15 0 % E
% Phe: 0 0 0 0 0 79 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 0 8 0 0 8 8 8 0 0 0 86 0 0 % I
% Lys: 0 0 0 58 8 0 0 0 0 0 0 0 0 8 8 % K
% Leu: 0 0 8 0 0 0 0 0 79 0 8 86 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 8 0 8 50 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 79 0 0 0 0 8 0 0 0 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 86 0 0 15 0 0 0 0 0 0 0 8 0 0 8 % R
% Ser: 0 0 0 0 22 0 8 79 0 0 50 0 0 43 0 % S
% Thr: 0 0 0 0 0 0 15 0 0 0 0 0 0 8 0 % T
% Val: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _