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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RFK All Species: 45.45
Human Site: S20 Identified Species: 76.92
UniProt: Q969G6 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969G6 NP_060809.2 155 17623 S20 V R G F G R G S K Q L G I P T
Chimpanzee Pan troglodytes XP_001149206 186 20421 Y51 G A M M G R G Y G S R A G S R
Rhesus Macaque Macaca mulatta XP_001092264 116 12991
Dog Lupus familis XP_541275 589 64931 S454 V R G F G R G S K Q L G I P T
Cat Felis silvestris
Mouse Mus musculus Q8CFV9 155 17418 S20 V R G F G R G S K Q L G I P T
Rat Rattus norvegicus NP_001014128 155 17462 S20 V R G F G R G S K Q L G I P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516422 191 21780 S20 V R G F G R G S K Q L G I P T
Chicken Gallus gallus NP_001026776 155 17559 S20 V R G F G R G S K E L G V P T
Frog Xenopus laevis NP_001079669 172 19314 S38 V K G F G R G S K E L G I P T
Zebra Danio Brachydanio rerio XP_689407 163 18463 S20 V R G F G R G S K D L G I P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76206 153 16967 S21 V R G F G R G S K E L G I P T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789693 130 14954 D12 Q N T N F P E D V V E N L P A
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001146905 398 43718 S253 I K G F G R G S K V L G I P T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q6M923 210 23418 S39 I S G F G R G S K E L G I P T
Conservation
Percent
Protein Identity: 100 73.1 70.3 25.1 N.A. 93.5 93.5 N.A. 57 78.7 65.6 73 N.A. 58.7 N.A. N.A. 53.5
Protein Similarity: 100 74.7 72.9 25.9 N.A. 98 98.7 N.A. 73.8 92.9 76.7 84.6 N.A. 76.1 N.A. N.A. 65.8
P-Site Identity: 100 20 0 100 N.A. 100 100 N.A. 100 86.6 86.6 93.3 N.A. 93.3 N.A. N.A. 6.6
P-Site Similarity: 100 20 0 100 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 100 N.A. N.A. 13.3
Percent
Protein Identity: N.A. 22.3 N.A. N.A. N.A. 31.9
Protein Similarity: N.A. 29.9 N.A. N.A. N.A. 46.6
P-Site Identity: N.A. 80 N.A. N.A. N.A. 80
P-Site Similarity: N.A. 93.3 N.A. N.A. N.A. 93.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 0 0 29 8 0 0 0 0 % E
% Phe: 0 0 0 79 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 79 0 86 0 86 0 8 0 0 79 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 15 0 0 0 0 0 0 0 0 0 0 0 72 0 0 % I
% Lys: 0 15 0 0 0 0 0 0 79 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 79 0 8 0 0 % L
% Met: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 0 0 0 86 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 36 0 0 0 0 0 % Q
% Arg: 0 58 0 0 0 86 0 0 0 0 8 0 0 0 8 % R
% Ser: 0 8 0 0 0 0 0 79 0 8 0 0 0 8 0 % S
% Thr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 79 % T
% Val: 65 0 0 0 0 0 0 0 8 15 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _