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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFK
All Species:
43.33
Human Site:
Y71
Identified Species:
73.33
UniProt:
Q969G6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969G6
NP_060809.2
155
17623
Y71
S
I
G
W
N
P
Y
Y
K
N
T
K
K
S
M
Chimpanzee
Pan troglodytes
XP_001149206
186
20421
Y102
S
I
G
W
N
P
Y
Y
K
N
T
K
K
S
M
Rhesus Macaque
Macaca mulatta
XP_001092264
116
12991
K48
V
G
S
G
D
V
H
K
M
V
V
G
I
G
W
Dog
Lupus familis
XP_541275
589
64931
Y505
S
I
G
W
N
P
Y
Y
K
N
T
K
K
S
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFV9
155
17418
Y71
S
I
G
W
N
P
Y
Y
K
N
V
K
K
S
M
Rat
Rattus norvegicus
NP_001014128
155
17462
Y71
S
I
G
W
N
P
Y
Y
K
N
V
K
K
S
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516422
191
21780
Y71
S
V
G
W
N
P
Y
Y
R
N
A
K
K
S
M
Chicken
Gallus gallus
NP_001026776
155
17559
Y71
S
I
G
W
N
P
F
Y
K
N
T
K
K
S
V
Frog
Xenopus laevis
NP_001079669
172
19314
Y89
S
I
G
W
N
P
F
Y
K
N
T
K
K
S
M
Zebra Danio
Brachydanio rerio
XP_689407
163
18463
Y71
S
I
G
W
N
P
Y
Y
K
N
T
K
K
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O76206
153
16967
Y72
S
I
G
W
N
P
F
Y
N
N
K
E
K
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789693
130
14954
M62
K
S
M
E
T
H
V
M
H
I
F
K
D
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146905
398
43718
F304
S
I
G
W
N
P
Y
F
D
N
T
E
K
T
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q6M923
210
23418
Y123
S
I
G
Y
N
P
F
Y
K
N
T
V
R
S
A
Conservation
Percent
Protein Identity:
100
73.1
70.3
25.1
N.A.
93.5
93.5
N.A.
57
78.7
65.6
73
N.A.
58.7
N.A.
N.A.
53.5
Protein Similarity:
100
74.7
72.9
25.9
N.A.
98
98.7
N.A.
73.8
92.9
76.7
84.6
N.A.
76.1
N.A.
N.A.
65.8
P-Site Identity:
100
100
0
100
N.A.
93.3
93.3
N.A.
80
86.6
93.3
100
N.A.
66.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
93.3
N.A.
93.3
100
100
100
N.A.
86.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
22.3
N.A.
N.A.
N.A.
31.9
Protein Similarity:
N.A.
29.9
N.A.
N.A.
N.A.
46.6
P-Site Identity:
N.A.
66.6
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
N.A.
93.3
N.A.
N.A.
N.A.
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
8
0
0
0
8
8
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
15
0
0
0
% E
% Phe:
0
0
0
0
0
0
29
8
0
0
8
0
0
0
8
% F
% Gly:
0
8
86
8
0
0
0
0
0
0
0
8
0
8
0
% G
% His:
0
0
0
0
0
8
8
0
8
0
0
0
0
0
0
% H
% Ile:
0
79
0
0
0
0
0
0
0
8
0
0
8
0
0
% I
% Lys:
8
0
0
0
0
0
0
8
65
0
8
72
79
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
8
8
0
0
0
0
0
58
% M
% Asn:
0
0
0
0
86
0
0
0
8
86
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
86
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% R
% Ser:
86
8
8
0
0
0
0
0
0
0
0
0
0
79
0
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
58
0
0
8
0
% T
% Val:
8
8
0
0
0
8
8
0
0
8
22
8
0
0
22
% V
% Trp:
0
0
0
79
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
8
0
0
58
79
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _