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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NKD1 All Species: 17.58
Human Site: S109 Identified Species: 48.33
UniProt: Q969G9 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969G9 NP_149110.1 470 52285 S109 E K K M E R V S E P C P G S K
Chimpanzee Pan troglodytes XP_520634 492 54450 S131 E K K M E R V S E P C P G S K
Rhesus Macaque Macaca mulatta XP_001086556 426 47195 R91 V S V E E D S R Q E W T F T L
Dog Lupus familis XP_544414 657 72223 S296 E K R R E K A S E S C P G S K
Cat Felis silvestris
Mouse Mus musculus Q99MH6 471 52373 S109 E K R M E R L S E P G Q A S K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519911 418 46562 S83 E K A D T F G S G D E K K R E
Chicken Gallus gallus XP_414094 469 52712 S115 E K K A E K E S D T R T G S K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q2TJA6 440 49953 T105 V E E R M Q G T E G S A T V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795739 590 65888 K114 Q E D S P S K K L P P S S P T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.4 76.1 63.6 N.A. 87 N.A. N.A. 43.1 64.4 N.A. 50 N.A. N.A. N.A. N.A. 21.6
Protein Similarity: 100 93.5 81.6 67.1 N.A. 90.8 N.A. N.A. 52.3 76.1 N.A. 62.7 N.A. N.A. N.A. N.A. 36.9
P-Site Identity: 100 100 6.6 66.6 N.A. 66.6 N.A. N.A. 20 53.3 N.A. 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 20 80 N.A. 80 N.A. N.A. 26.6 66.6 N.A. 33.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 12 0 0 12 0 0 0 0 12 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 34 0 0 0 0 % C
% Asp: 0 0 12 12 0 12 0 0 12 12 0 0 0 0 0 % D
% Glu: 67 23 12 12 67 0 12 0 56 12 12 0 0 0 12 % E
% Phe: 0 0 0 0 0 12 0 0 0 0 0 0 12 0 0 % F
% Gly: 0 0 0 0 0 0 23 0 12 12 12 0 45 0 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 67 34 0 0 23 12 12 0 0 0 12 12 0 56 % K
% Leu: 0 0 0 0 0 0 12 0 12 0 0 0 0 0 12 % L
% Met: 0 0 0 34 12 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 12 0 0 0 0 45 12 34 0 12 0 % P
% Gln: 12 0 0 0 0 12 0 0 12 0 0 12 0 0 0 % Q
% Arg: 0 0 23 23 0 34 0 12 0 0 12 0 0 12 0 % R
% Ser: 0 12 0 12 0 12 12 67 0 12 12 12 12 56 0 % S
% Thr: 0 0 0 0 12 0 0 12 0 12 0 23 12 12 12 % T
% Val: 23 0 12 0 0 0 23 0 0 0 0 0 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _