KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW7
All Species:
26.67
Human Site:
S546
Identified Species:
45.13
UniProt:
Q969H0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969H0
NP_001013433.1
707
79663
S546
G
H
T
N
R
V
Y
S
L
Q
F
D
G
I
H
Chimpanzee
Pan troglodytes
Q5IS43
410
46712
N254
T
L
I
A
S
C
S
N
D
Q
T
V
R
V
W
Rhesus Macaque
Macaca mulatta
XP_001084190
707
79630
S546
G
H
T
N
R
V
Y
S
L
Q
F
D
G
I
H
Dog
Lupus familis
XP_532689
589
66075
G433
V
Y
S
L
Q
F
D
G
I
H
V
V
S
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBV4
629
70529
G473
V
Y
S
L
Q
F
D
G
I
H
V
V
S
G
S
Rat
Rattus norvegicus
Q5BK30
415
45841
G259
R
K
V
H
T
L
I
G
H
C
A
E
I
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514172
706
79789
S545
G
H
T
N
R
V
Y
S
L
Q
F
D
G
I
H
Chicken
Gallus gallus
XP_420447
702
79452
S541
G
H
T
N
R
V
Y
S
L
Q
F
D
G
I
H
Frog
Xenopus laevis
Q91854
518
59489
D362
R
A
A
V
N
V
V
D
F
D
D
K
Y
I
V
Zebra Danio
Brachydanio rerio
XP_693393
605
68178
G449
V
Y
S
L
Q
F
D
G
I
H
V
V
S
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZF4
1326
141343
S1160
G
H
T
N
R
V
Y
S
L
Q
F
D
G
L
H
Honey Bee
Apis mellifera
XP_396532
696
77358
S535
G
H
T
N
R
V
Y
S
L
Q
F
D
G
V
H
Nematode Worm
Caenorhab. elegans
Q93794
587
65293
S431
L
L
F
E
S
E
R
S
I
V
C
S
G
S
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07834
779
86072
S575
G
H
T
D
R
I
Y
S
T
I
Y
D
H
E
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.3
99.8
79.3
N.A.
79.4
20.6
N.A.
96.7
94
25
75.1
N.A.
37.1
59.9
37.3
N.A.
Protein Similarity:
100
33.9
100
81.1
N.A.
82.1
34.7
N.A.
98.4
96.7
42.5
78.9
N.A.
45.2
72.1
53
N.A.
P-Site Identity:
100
6.6
100
0
N.A.
0
0
N.A.
100
100
13.3
0
N.A.
93.3
93.3
13.3
N.A.
P-Site Similarity:
100
20
100
26.6
N.A.
26.6
20
N.A.
100
100
13.3
26.6
N.A.
100
100
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
8
8
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
22
8
8
8
8
50
0
0
0
% D
% Glu:
0
0
0
8
0
8
0
0
0
0
0
8
0
8
0
% E
% Phe:
0
0
8
0
0
22
0
0
8
0
43
0
0
0
0
% F
% Gly:
50
0
0
0
0
0
0
29
0
0
0
0
50
22
0
% G
% His:
0
50
0
8
0
0
0
0
8
22
0
0
8
0
43
% H
% Ile:
0
0
8
0
0
8
8
0
29
8
0
0
8
36
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
8
15
0
22
0
8
0
0
43
0
0
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
43
8
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
22
0
0
0
0
50
0
0
0
0
0
% Q
% Arg:
15
0
0
0
50
0
8
0
0
0
0
0
8
0
8
% R
% Ser:
0
0
22
0
15
0
8
58
0
0
0
8
22
15
29
% S
% Thr:
8
0
50
0
8
0
0
0
8
0
8
0
0
0
0
% T
% Val:
22
0
8
8
0
50
8
0
0
8
22
29
0
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
22
0
0
0
0
50
0
0
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _