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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW7
All Species:
16.67
Human Site:
S91
Identified Species:
28.21
UniProt:
Q969H0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969H0
NP_001013433.1
707
79663
S91
F
I
S
V
D
E
D
S
S
G
N
Q
E
E
Q
Chimpanzee
Pan troglodytes
Q5IS43
410
46712
Rhesus Macaque
Macaca mulatta
XP_001084190
707
79630
S91
F
I
S
V
D
E
D
S
S
G
N
Q
E
E
Q
Dog
Lupus familis
XP_532689
589
66075
Q28
A
K
E
P
L
P
H
Q
T
V
M
K
I
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBV4
629
70529
S68
R
T
H
G
G
T
E
S
L
K
G
K
N
T
E
Rat
Rattus norvegicus
Q5BK30
415
45841
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514172
706
79789
S89
F
I
A
V
D
E
E
S
T
G
N
Q
E
D
Q
Chicken
Gallus gallus
XP_420447
702
79452
S90
L
I
T
V
D
E
E
S
T
C
N
Q
E
E
D
Frog
Xenopus laevis
Q91854
518
59489
Zebra Danio
Brachydanio rerio
XP_693393
605
68178
E44
L
E
L
A
D
P
K
E
V
T
K
E
P
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZF4
1326
141343
R421
W
P
S
S
S
N
G
R
T
V
S
S
D
S
K
Honey Bee
Apis mellifera
XP_396532
696
77358
S88
S
S
L
E
P
M
H
S
L
L
A
Q
D
E
E
Nematode Worm
Caenorhab. elegans
Q93794
587
65293
D26
Q
E
P
V
T
D
N
D
M
E
Y
N
D
N
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07834
779
86072
T100
H
P
V
N
L
Q
N
T
G
A
A
S
V
D
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.3
99.8
79.3
N.A.
79.4
20.6
N.A.
96.7
94
25
75.1
N.A.
37.1
59.9
37.3
N.A.
Protein Similarity:
100
33.9
100
81.1
N.A.
82.1
34.7
N.A.
98.4
96.7
42.5
78.9
N.A.
45.2
72.1
53
N.A.
P-Site Identity:
100
0
100
0
N.A.
6.6
0
N.A.
73.3
60
0
6.6
N.A.
6.6
20
6.6
N.A.
P-Site Similarity:
100
0
100
13.3
N.A.
26.6
0
N.A.
100
80
0
13.3
N.A.
40
33.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
0
0
0
0
8
15
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
36
8
15
8
0
0
0
0
22
15
8
% D
% Glu:
0
15
8
8
0
29
22
8
0
8
0
8
29
29
15
% E
% Phe:
22
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
8
8
0
8
0
8
22
8
0
0
0
8
% G
% His:
8
0
8
0
0
0
15
0
0
0
0
0
0
0
0
% H
% Ile:
0
29
0
0
0
0
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
8
0
0
0
0
8
0
0
8
8
15
0
0
8
% K
% Leu:
15
0
15
0
15
0
0
0
15
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
8
0
8
0
0
0
0
% M
% Asn:
0
0
0
8
0
8
15
0
0
0
29
8
8
8
8
% N
% Pro:
0
15
8
8
8
15
0
0
0
0
0
0
8
0
8
% P
% Gln:
8
0
0
0
0
8
0
8
0
0
0
36
0
0
22
% Q
% Arg:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
8
22
8
8
0
0
43
15
0
8
15
0
8
8
% S
% Thr:
0
8
8
0
8
8
0
8
29
8
0
0
0
8
0
% T
% Val:
0
0
8
36
0
0
0
0
8
15
0
0
8
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _