KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW7
All Species:
7.88
Human Site:
T53
Identified Species:
13.33
UniProt:
Q969H0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969H0
NP_001013433.1
707
79663
T53
R
Q
Q
E
E
E
H
T
A
R
N
G
E
V
V
Chimpanzee
Pan troglodytes
Q5IS43
410
46712
Rhesus Macaque
Macaca mulatta
XP_001084190
707
79630
T53
R
Q
Q
E
E
E
H
T
A
R
N
G
E
V
V
Dog
Lupus familis
XP_532689
589
66075
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBV4
629
70529
A34
L
P
N
L
P
F
L
A
C
L
S
M
S
T
L
Rat
Rattus norvegicus
Q5BK30
415
45841
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514172
706
79789
I51
R
Q
Q
E
E
E
H
I
V
R
N
G
E
L
V
Chicken
Gallus gallus
XP_420447
702
79452
I53
Q
Q
Q
E
E
Q
H
I
G
R
N
G
E
I
R
Frog
Xenopus laevis
Q91854
518
59489
Zebra Danio
Brachydanio rerio
XP_693393
605
68178
F10
R
H
C
P
I
P
R
F
S
S
G
P
R
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZF4
1326
141343
R370
R
D
F
E
T
E
Q
R
L
T
G
G
I
I
L
Honey Bee
Apis mellifera
XP_396532
696
77358
S52
K
P
V
M
S
V
P
S
S
S
S
N
K
I
T
Nematode Worm
Caenorhab. elegans
Q93794
587
65293
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07834
779
86072
Y63
G
E
E
D
I
D
E
Y
Q
R
K
R
A
A
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.3
99.8
79.3
N.A.
79.4
20.6
N.A.
96.7
94
25
75.1
N.A.
37.1
59.9
37.3
N.A.
Protein Similarity:
100
33.9
100
81.1
N.A.
82.1
34.7
N.A.
98.4
96.7
42.5
78.9
N.A.
45.2
72.1
53
N.A.
P-Site Identity:
100
0
100
0
N.A.
0
0
N.A.
80
60
0
6.6
N.A.
26.6
0
0
N.A.
P-Site Similarity:
100
0
100
0
N.A.
13.3
0
N.A.
86.6
80
0
13.3
N.A.
40
40
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
15
0
0
0
8
8
0
% A
% Cys:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
8
36
29
29
8
0
0
0
0
0
29
0
0
% E
% Phe:
0
0
8
0
0
8
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
8
0
15
36
0
0
8
% G
% His:
0
8
0
0
0
0
29
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
15
0
0
15
0
0
0
0
8
22
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
8
0
8
0
8
% K
% Leu:
8
0
0
8
0
0
8
0
8
8
0
0
0
8
15
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
29
8
0
0
0
% N
% Pro:
0
15
0
8
8
8
8
0
0
0
0
8
0
0
0
% P
% Gln:
8
29
29
0
0
8
8
0
8
0
0
0
0
0
0
% Q
% Arg:
36
0
0
0
0
0
8
8
0
36
0
8
8
8
8
% R
% Ser:
0
0
0
0
8
0
0
8
15
15
15
0
8
0
0
% S
% Thr:
0
0
0
0
8
0
0
15
0
8
0
0
0
8
8
% T
% Val:
0
0
8
0
0
8
0
0
8
0
0
0
0
15
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _