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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW7
All Species:
15.15
Human Site:
T530
Identified Species:
25.64
UniProt:
Q969H0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969H0
NP_001013433.1
707
79663
T530
V
K
V
W
D
P
E
T
E
T
C
L
H
T
L
Chimpanzee
Pan troglodytes
Q5IS43
410
46712
R238
T
G
H
R
E
W
V
R
M
V
R
P
N
Q
D
Rhesus Macaque
Macaca mulatta
XP_001084190
707
79630
T530
V
K
V
W
D
P
E
T
E
T
C
L
H
T
L
Dog
Lupus familis
XP_532689
589
66075
H417
P
E
T
E
T
C
L
H
T
L
Q
G
H
T
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBV4
629
70529
H457
P
E
T
E
T
C
L
H
T
L
Q
G
H
T
N
Rat
Rattus norvegicus
Q5BK30
415
45841
V243
T
G
S
F
D
H
T
V
V
V
W
D
A
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514172
706
79789
T529
V
K
V
W
D
P
E
T
E
T
C
L
H
T
L
Chicken
Gallus gallus
XP_420447
702
79452
T525
V
K
V
W
D
P
E
T
E
T
C
L
H
T
L
Frog
Xenopus laevis
Q91854
518
59489
T346
M
A
S
A
T
D
I
T
L
R
R
V
L
V
G
Zebra Danio
Brachydanio rerio
XP_693393
605
68178
H433
P
E
T
E
T
C
L
H
T
L
Q
G
H
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZF4
1326
141343
R1144
V
K
I
W
H
P
E
R
Q
E
C
L
H
T
L
Honey Bee
Apis mellifera
XP_396532
696
77358
R519
V
K
V
W
N
P
E
R
E
E
C
L
H
T
L
Nematode Worm
Caenorhab. elegans
Q93794
587
65293
T415
G
R
C
I
R
T
L
T
G
H
N
N
R
V
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07834
779
86072
Q559
L
I
V
W
D
V
A
Q
M
K
C
L
Y
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.3
99.8
79.3
N.A.
79.4
20.6
N.A.
96.7
94
25
75.1
N.A.
37.1
59.9
37.3
N.A.
Protein Similarity:
100
33.9
100
81.1
N.A.
82.1
34.7
N.A.
98.4
96.7
42.5
78.9
N.A.
45.2
72.1
53
N.A.
P-Site Identity:
100
0
100
13.3
N.A.
13.3
6.6
N.A.
100
100
6.6
13.3
N.A.
66.6
80
6.6
N.A.
P-Site Similarity:
100
13.3
100
20
N.A.
20
20
N.A.
100
100
20
20
N.A.
80
86.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
8
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
8
0
0
22
0
0
0
0
50
0
0
0
0
% C
% Asp:
0
0
0
0
43
8
0
0
0
0
0
8
0
0
8
% D
% Glu:
0
22
0
22
8
0
43
0
36
15
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
15
0
0
0
0
0
0
8
0
0
22
0
0
8
% G
% His:
0
0
8
0
8
8
0
22
0
8
0
0
65
0
0
% H
% Ile:
0
8
8
8
0
0
8
0
0
0
0
0
0
8
0
% I
% Lys:
0
43
0
0
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
29
0
8
22
0
50
8
0
50
% L
% Met:
8
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
8
8
8
0
22
% N
% Pro:
22
0
0
0
0
43
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
8
0
22
0
0
8
0
% Q
% Arg:
0
8
0
8
8
0
0
22
0
8
15
0
8
0
0
% R
% Ser:
0
0
15
0
0
0
0
0
0
0
0
0
0
8
0
% S
% Thr:
15
0
22
0
29
8
8
43
22
29
0
0
0
65
8
% T
% Val:
43
0
43
0
0
8
8
8
8
15
0
8
0
15
0
% V
% Trp:
0
0
0
50
0
8
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _