KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW7
All Species:
21.21
Human Site:
T576
Identified Species:
35.9
UniProt:
Q969H0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969H0
NP_001013433.1
707
79663
T576
E
T
G
N
C
I
H
T
L
T
G
H
Q
S
L
Chimpanzee
Pan troglodytes
Q5IS43
410
46712
W284
H
V
V
E
C
I
S
W
A
P
E
S
S
Y
S
Rhesus Macaque
Macaca mulatta
XP_001084190
707
79630
T576
E
T
G
N
C
I
H
T
L
T
G
H
Q
S
L
Dog
Lupus familis
XP_532689
589
66075
Q463
I
H
T
L
T
G
H
Q
S
L
T
S
G
M
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBV4
629
70529
Q503
I
H
T
L
T
G
H
Q
S
L
T
S
G
M
E
Rat
Rattus norvegicus
Q5BK30
415
45841
D289
D
K
T
C
M
L
W
D
A
T
S
G
K
C
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514172
706
79789
T575
E
T
G
N
C
I
H
T
L
T
G
H
Q
S
L
Chicken
Gallus gallus
XP_420447
702
79452
T571
E
T
G
N
C
I
H
T
L
T
G
H
Q
S
L
Frog
Xenopus laevis
Q91854
518
59489
N392
C
E
F
V
R
T
L
N
G
H
K
R
G
I
A
Zebra Danio
Brachydanio rerio
XP_693393
605
68178
Q479
I
H
T
L
T
G
H
Q
S
L
T
S
G
M
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZF4
1326
141343
T1190
E
T
G
N
C
K
H
T
L
M
G
H
Q
S
L
Honey Bee
Apis mellifera
XP_396532
696
77358
T565
E
T
G
A
C
R
H
T
L
M
G
H
Q
S
L
Nematode Worm
Caenorhab. elegans
Q93794
587
65293
G461
E
C
V
A
L
L
Q
G
H
T
S
L
T
S
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07834
779
86072
N605
D
L
E
N
I
W
N
N
G
E
C
S
Y
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.3
99.8
79.3
N.A.
79.4
20.6
N.A.
96.7
94
25
75.1
N.A.
37.1
59.9
37.3
N.A.
Protein Similarity:
100
33.9
100
81.1
N.A.
82.1
34.7
N.A.
98.4
96.7
42.5
78.9
N.A.
45.2
72.1
53
N.A.
P-Site Identity:
100
13.3
100
6.6
N.A.
6.6
6.6
N.A.
100
100
0
6.6
N.A.
86.6
80
20
N.A.
P-Site Similarity:
100
13.3
100
6.6
N.A.
6.6
33.3
N.A.
100
100
0
6.6
N.A.
86.6
80
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
0
0
0
0
15
0
0
0
0
8
8
% A
% Cys:
8
8
0
8
50
0
0
0
0
0
8
0
0
8
0
% C
% Asp:
15
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
50
8
8
8
0
0
0
0
0
8
8
0
0
0
22
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
43
0
0
22
0
8
15
0
43
8
29
0
8
% G
% His:
8
22
0
0
0
0
65
0
8
8
0
43
0
0
0
% H
% Ile:
22
0
0
0
8
36
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
8
0
0
0
8
0
0
0
0
8
0
8
0
0
% K
% Leu:
0
8
0
22
8
15
8
0
43
22
0
8
0
0
43
% L
% Met:
0
0
0
0
8
0
0
0
0
15
0
0
0
22
0
% M
% Asn:
0
0
0
43
0
0
8
15
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
22
0
0
0
0
43
0
0
% Q
% Arg:
0
0
0
0
8
8
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
0
22
0
15
36
8
50
8
% S
% Thr:
0
43
29
0
22
8
0
43
0
43
22
0
8
0
8
% T
% Val:
0
8
15
8
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
8
8
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _