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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CNKSR1
All Species:
10.3
Human Site:
S535
Identified Species:
28.33
UniProt:
Q969H4
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969H4
NP_006305.2
720
79706
S535
D
D
E
A
G
S
H
S
A
S
P
S
P
A
Q
Chimpanzee
Pan troglodytes
XP_524626
675
75055
S490
D
D
E
A
G
S
H
S
A
S
P
S
P
A
Q
Rhesus Macaque
Macaca mulatta
XP_001086538
1034
117546
S702
P
S
T
P
K
Q
D
S
P
P
P
P
Y
D
T
Dog
Lupus familis
XP_544485
717
79583
S532
D
D
D
A
G
S
R
S
A
S
P
C
P
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q80YA9
1032
117378
S702
P
S
T
P
K
Q
D
S
P
P
P
P
Y
D
T
Rat
Rattus norvegicus
Q9Z1T4
1032
117372
S702
P
S
T
P
K
Q
D
S
P
P
P
P
Y
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519265
207
23155
G37
S
G
R
H
F
V
S
G
T
S
P
E
F
L
A
Chicken
Gallus gallus
XP_417698
294
33261
E125
E
A
E
D
P
D
D
E
S
P
R
H
G
C
D
Frog
Xenopus laevis
NP_001085442
981
110674
K653
V
D
T
P
S
T
P
K
Q
D
S
P
P
P
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
25.5
78.8
N.A.
25.8
25.7
N.A.
21.5
22.2
26.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.4
41
84.3
N.A.
40.9
40.8
N.A.
24.7
31.2
41.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
80
N.A.
13.3
13.3
N.A.
13.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
86.6
N.A.
13.3
13.3
N.A.
13.3
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
34
0
0
0
0
34
0
0
0
0
34
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
12
0
12
0
% C
% Asp:
34
45
12
12
0
12
45
0
0
12
0
0
0
34
12
% D
% Glu:
12
0
34
0
0
0
0
12
0
0
0
12
0
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
12
0
0
34
0
0
12
0
0
0
0
12
0
0
% G
% His:
0
0
0
12
0
0
23
0
0
0
0
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
34
0
0
12
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
34
0
0
45
12
0
12
0
34
45
78
45
45
12
12
% P
% Gln:
0
0
0
0
0
34
0
0
12
0
0
0
0
0
34
% Q
% Arg:
0
0
12
0
0
0
12
0
0
0
12
0
0
0
0
% R
% Ser:
12
34
0
0
12
34
12
67
12
45
12
23
0
0
0
% S
% Thr:
0
0
45
0
0
12
0
0
12
0
0
0
0
0
34
% T
% Val:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
34
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _