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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LOH12CR1
All Species:
21.21
Human Site:
S130
Identified Species:
38.89
UniProt:
Q969J3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969J3
NP_477517.1
196
22222
S130
L
S
V
E
T
L
F
S
F
M
Q
E
R
Q
K
Chimpanzee
Pan troglodytes
XP_001139139
148
16996
M84
V
E
T
L
F
S
F
M
Q
E
R
Q
K
R
Y
Rhesus Macaque
Macaca mulatta
XP_001084966
196
22202
S130
L
S
V
E
T
L
F
S
F
M
Q
E
R
Q
K
Dog
Lupus familis
XP_543811
196
22271
S130
L
S
V
E
T
L
F
S
F
M
Q
E
R
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D920
195
22102
C130
L
S
V
E
T
L
F
C
F
M
Q
E
R
Q
K
Rat
Rattus norvegicus
NP_001102120
195
22158
C130
L
S
V
E
T
L
F
C
F
M
Q
E
R
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508519
232
25744
G166
L
S
V
E
T
L
F
G
F
M
Q
E
R
Q
K
Chicken
Gallus gallus
Q5ZJA9
185
20916
S119
L
S
V
E
T
L
Y
S
F
M
Q
E
R
Q
K
Frog
Xenopus laevis
Q5PPY2
196
22036
S130
S
S
V
D
G
L
Y
S
L
M
Q
E
R
Q
K
Zebra Danio
Brachydanio rerio
Q5XIX8
207
23526
S130
L
S
V
E
A
L
F
S
I
M
Q
E
R
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572759
349
37300
A266
N
S
I
T
T
L
F
A
G
F
V
D
M
Q
K
Honey Bee
Apis mellifera
XP_393997
269
30061
K205
N
I
E
P
E
V
T
K
I
L
N
L
A
T
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788867
246
27283
Q181
A
I
I
H
S
I
M
Q
S
M
A
E
R
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
98.4
95.9
N.A.
94.9
93.8
N.A.
71.9
82.1
80
74.4
N.A.
26
30.1
N.A.
43
Protein Similarity:
100
75.5
99.4
97.4
N.A.
97.4
97.4
N.A.
77.5
88.7
90.8
83.5
N.A.
38.6
46
N.A.
58.1
P-Site Identity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
93.3
93.3
66.6
86.6
N.A.
40
0
N.A.
33.3
P-Site Similarity:
100
40
100
100
N.A.
93.3
93.3
N.A.
93.3
100
80
86.6
N.A.
60
20
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
8
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
8
8
62
8
0
0
0
0
8
0
77
0
0
8
% E
% Phe:
0
0
0
0
8
0
70
0
54
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
8
8
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
16
0
0
8
0
0
16
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
85
% K
% Leu:
62
0
0
8
0
77
0
0
8
8
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
8
8
0
77
0
0
8
0
0
% M
% Asn:
16
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
8
0
70
8
0
85
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
77
8
0
% R
% Ser:
8
77
0
0
8
8
0
47
8
0
0
0
0
0
0
% S
% Thr:
0
0
8
8
62
0
8
0
0
0
0
0
0
8
0
% T
% Val:
8
0
70
0
0
8
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _