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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LOH12CR1
All Species:
27.27
Human Site:
S175
Identified Species:
50
UniProt:
Q969J3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969J3
NP_477517.1
196
22222
S175
P
L
L
D
R
L
N
S
M
L
P
E
G
E
R
Chimpanzee
Pan troglodytes
XP_001139139
148
16996
L129
L
D
R
L
N
S
M
L
P
E
G
E
R
L
E
Rhesus Macaque
Macaca mulatta
XP_001084966
196
22202
S175
P
L
L
D
R
L
N
S
L
L
P
E
S
E
R
Dog
Lupus familis
XP_543811
196
22271
S175
P
L
M
E
R
L
N
S
M
L
P
E
G
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D920
195
22102
S175
P
L
M
E
R
L
N
S
M
L
P
E
A
E
R
Rat
Rattus norvegicus
NP_001102120
195
22158
S175
P
L
M
E
R
L
N
S
M
L
P
E
A
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508519
232
25744
C211
P
L
V
D
R
L
N
C
L
L
P
Q
S
E
R
Chicken
Gallus gallus
Q5ZJA9
185
20916
S164
P
L
M
E
R
L
N
S
M
L
P
E
S
E
Q
Frog
Xenopus laevis
Q5PPY2
196
22036
I175
P
L
M
E
K
L
N
I
M
L
P
E
G
E
R
Zebra Danio
Brachydanio rerio
Q5XIX8
207
23526
N175
P
L
M
E
R
L
N
N
M
L
P
E
S
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572759
349
37300
N311
A
S
L
E
A
I
N
N
F
L
D
D
E
D
R
Honey Bee
Apis mellifera
XP_393997
269
30061
T250
Q
T
L
E
S
L
E
T
L
N
N
L
L
P
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788867
246
27283
S226
P
L
M
D
R
L
N
S
V
L
P
D
A
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
98.4
95.9
N.A.
94.9
93.8
N.A.
71.9
82.1
80
74.4
N.A.
26
30.1
N.A.
43
Protein Similarity:
100
75.5
99.4
97.4
N.A.
97.4
97.4
N.A.
77.5
88.7
90.8
83.5
N.A.
38.6
46
N.A.
58.1
P-Site Identity:
100
6.6
86.6
86.6
N.A.
80
80
N.A.
66.6
73.3
73.3
60
N.A.
26.6
13.3
N.A.
73.3
P-Site Similarity:
100
6.6
93.3
100
N.A.
93.3
93.3
N.A.
86.6
93.3
93.3
80
N.A.
60
33.3
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
0
0
0
0
0
24
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
31
0
0
0
0
0
0
8
16
0
8
0
% D
% Glu:
0
0
0
62
0
0
8
0
0
8
0
70
8
70
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
24
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
77
31
8
0
85
0
8
24
85
0
8
8
16
0
% L
% Met:
0
0
54
0
0
0
8
0
54
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
85
16
0
8
8
0
0
0
0
% N
% Pro:
77
0
0
0
0
0
0
0
8
0
77
0
0
8
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% Q
% Arg:
0
0
8
0
70
0
0
0
0
0
0
0
8
0
70
% R
% Ser:
0
8
0
0
8
8
0
54
0
0
0
0
31
0
0
% S
% Thr:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _