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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LOH12CR1 All Species: 24.55
Human Site: T21 Identified Species: 45
UniProt: Q969J3 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969J3 NP_477517.1 196 22222 T21 N D L N S S V T P S P A K H R
Chimpanzee Pan troglodytes XP_001139139 148 16996
Rhesus Macaque Macaca mulatta XP_001084966 196 22202 T21 N D L N S S V T P S P A K H R
Dog Lupus familis XP_543811 196 22271 T21 N D L N P S V T P S P A K H R
Cat Felis silvestris
Mouse Mus musculus Q9D920 195 22102 T21 G D L N A S V T P S P A K H R
Rat Rattus norvegicus NP_001102120 195 22158 T21 G D L N A S V T P S P A K H R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508519 232 25744 S57 P P E K C R V S P S P A K Q R
Chicken Gallus gallus Q5ZJA9 185 20916 V25 A K M D D I V V V A P G T Q S
Frog Xenopus laevis Q5PPY2 196 22036 S21 N D V S S S A S P S P A K Q K
Zebra Danio Brachydanio rerio Q5XIX8 207 23526 V21 S D F S A S V V P S P A K H R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572759 349 37300 K157 S G L T S A V K P K R P Q S T
Honey Bee Apis mellifera XP_393997 269 30061 N21 T N A N R T R N I P L R R G K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788867 246 27283 T21 D A P I E S T T G P T P A A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.4 98.4 95.9 N.A. 94.9 93.8 N.A. 71.9 82.1 80 74.4 N.A. 26 30.1 N.A. 43
Protein Similarity: 100 75.5 99.4 97.4 N.A. 97.4 97.4 N.A. 77.5 88.7 90.8 83.5 N.A. 38.6 46 N.A. 58.1
P-Site Identity: 100 0 100 93.3 N.A. 86.6 86.6 N.A. 46.6 13.3 60 66.6 N.A. 26.6 6.6 N.A. 13.3
P-Site Similarity: 100 0 100 93.3 N.A. 93.3 93.3 N.A. 53.3 33.3 86.6 86.6 N.A. 46.6 33.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 24 8 8 0 0 8 0 62 8 8 8 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 54 0 8 8 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 16 8 0 0 0 0 0 0 8 0 0 8 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 % H
% Ile: 0 0 0 8 0 8 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 8 0 8 0 0 0 8 0 8 0 0 62 0 16 % K
% Leu: 0 0 47 0 0 0 0 0 0 0 8 0 0 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 31 8 0 47 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 8 8 8 0 8 0 0 0 70 16 70 16 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 8 24 0 % Q
% Arg: 0 0 0 0 8 8 8 0 0 0 8 8 8 0 54 % R
% Ser: 16 0 0 16 31 62 0 16 0 62 0 0 0 8 8 % S
% Thr: 8 0 0 8 0 8 8 47 0 0 8 0 8 0 8 % T
% Val: 0 0 8 0 0 0 70 16 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _