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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LOH12CR1 All Species: 39.39
Human Site: Y142 Identified Species: 72.22
UniProt: Q969J3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969J3 NP_477517.1 196 22222 Y142 R Q K R Y A K Y A E Q I Q K V
Chimpanzee Pan troglodytes XP_001139139 148 16996 E96 K R Y A K Y A E Q I Q K V N E
Rhesus Macaque Macaca mulatta XP_001084966 196 22202 Y142 R Q K R Y A K Y A E Q I Q K V
Dog Lupus familis XP_543811 196 22271 Y142 R Q K R Y A K Y A E Q I Q K V
Cat Felis silvestris
Mouse Mus musculus Q9D920 195 22102 Y142 R Q K R Y A K Y A E Q I Q K V
Rat Rattus norvegicus NP_001102120 195 22158 Y142 R Q K R Y A K Y A E Q I Q K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508519 232 25744 Y178 R Q K R Y A K Y A E Q I Q K V
Chicken Gallus gallus Q5ZJA9 185 20916 Y131 R Q K K Y A K Y A E Q I Q K V
Frog Xenopus laevis Q5PPY2 196 22036 Y142 R Q K R F A K Y A E Q I Q K V
Zebra Danio Brachydanio rerio Q5XIX8 207 23526 Y142 R Q K R Y A K Y A E Q I Q K V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572759 349 37300 Y278 M Q K T Y A S Y A E Q F A K I
Honey Bee Apis mellifera XP_393997 269 30061 F217 A T E R Q K K F A K F A E Q L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788867 246 27283 H193 R Q K R F A K H A E Q I Q K I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.4 98.4 95.9 N.A. 94.9 93.8 N.A. 71.9 82.1 80 74.4 N.A. 26 30.1 N.A. 43
Protein Similarity: 100 75.5 99.4 97.4 N.A. 97.4 97.4 N.A. 77.5 88.7 90.8 83.5 N.A. 38.6 46 N.A. 58.1
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 100 93.3 93.3 100 N.A. 60 20 N.A. 80
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 66.6 60 N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 0 85 8 0 93 0 0 8 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 0 0 0 8 0 85 0 0 8 0 8 % E
% Phe: 0 0 0 0 16 0 0 8 0 0 8 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 77 0 0 16 % I
% Lys: 8 0 85 8 8 8 85 0 0 8 0 8 0 85 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 85 0 0 8 0 0 0 8 0 93 0 77 8 0 % Q
% Arg: 77 8 0 77 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % S
% Thr: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 70 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 70 8 0 77 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _