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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF34 All Species: 25.76
Human Site: S254 Identified Species: 62.96
UniProt: Q969K3 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969K3 NP_079402.2 372 41641 S254 S K E R V R A S L S D L S S L
Chimpanzee Pan troglodytes Q95M72 236 27118 D127 R M G F D F K D V K K I M E E
Rhesus Macaque Macaca mulatta XP_001095309 376 42125 S258 S K E R A R A S L S D L S S L
Dog Lupus familis XP_534667 375 41845 S257 S E K R V R A S L S D L S S L
Cat Felis silvestris
Mouse Mus musculus Q99KR6 376 42011 S258 S K K K A R A S L S D L S S L
Rat Rattus norvegicus Q6AYH3 381 42662 S263 S K K K A R A S L S D L S S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510920 359 39885 S241 S R K R V R A S L S D L S S L
Chicken Gallus gallus NP_001006188 346 37954 L236 S L S D I S S L D D I E G L S
Frog Xenopus laevis NP_001085293 355 39318 D237 S D L S V L E D I D A L T I R
Zebra Danio Brachydanio rerio NP_001025239 363 40572 S237 T R R R A R A S L S D L S S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 21.2 97.6 90.1 N.A. 88.3 86.3 N.A. 80.3 72.8 67.4 63.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 32.5 98.1 93.5 N.A. 93.6 92.3 N.A. 87.3 80.3 77.6 73.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 93.3 86.6 N.A. 80 80 N.A. 86.6 6.6 20 73.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 93.3 100 N.A. 93.3 93.3 N.A. 100 20 33.3 86.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 40 0 70 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 10 10 0 0 20 10 20 70 0 0 0 0 % D
% Glu: 0 10 20 0 0 0 10 0 0 0 0 10 0 10 10 % E
% Phe: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 10 0 10 10 0 10 0 % I
% Lys: 0 40 40 20 0 0 10 0 0 10 10 0 0 0 0 % K
% Leu: 0 10 10 0 0 10 0 10 70 0 0 80 0 10 70 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 20 10 50 0 70 0 0 0 0 0 0 0 0 10 % R
% Ser: 80 0 10 10 0 10 10 70 0 70 0 0 70 70 10 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % T
% Val: 0 0 0 0 40 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _