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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABTB1 All Species: 27.58
Human Site: T434 Identified Species: 60.67
UniProt: Q969K4 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969K4 NP_115937.1 478 53979 T434 A V A A R Q E T D S I P L V D
Chimpanzee Pan troglodytes XP_526451 397 44612 P357 R Q E T D S I P L V D D I R F
Rhesus Macaque Macaca mulatta XP_001099270 486 54776 T442 A V A A R Q E T D S I P L V D
Dog Lupus familis XP_851631 478 54068 T434 A V A A R Q E T D S I P L V D
Cat Felis silvestris
Mouse Mus musculus Q99LJ2 478 54039 T434 A V A A R Q E T D S I P L V D
Rat Rattus norvegicus Q5XIU1 478 54046 T434 A V A A R Q E T D S I P L V D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506861 650 73483 T606 A V A E R Q E T D S I P L V D
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788155 481 55617 V437 S V E N R E E V D S I T I I D
Poplar Tree Populus trichocarpa XP_002321173 587 66396 A526 A P S A P G A A L N T D Q G N
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_178551 578 66049 S511 S L R T T V P S A P G A M M T
Baker's Yeast Sacchar. cerevisiae P40560 513 59713 T451 R I S L R Q E T D T I E L V D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.2 93.2 95.6 N.A. 94.3 94.5 N.A. 53.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 45.7
Protein Similarity: 100 83 95.4 97.6 N.A. 96.6 96.8 N.A. 61.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 67.7
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 93.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 93.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: 28.6 N.A. N.A. 27.5 26.1 N.A.
Protein Similarity: 43.6 N.A. N.A. 43.4 46.2 N.A.
P-Site Identity: 13.3 N.A. N.A. 0 60 N.A.
P-Site Similarity: 33.3 N.A. N.A. 33.3 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 64 0 55 55 0 0 10 10 10 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 73 0 10 19 0 0 73 % D
% Glu: 0 0 19 10 0 10 73 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 10 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 10 0 0 0 73 0 19 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 10 0 0 0 0 19 0 0 0 64 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 10 % N
% Pro: 0 10 0 0 10 0 10 10 0 10 0 55 0 0 0 % P
% Gln: 0 10 0 0 0 64 0 0 0 0 0 0 10 0 0 % Q
% Arg: 19 0 10 0 73 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 19 0 19 0 0 10 0 10 0 64 0 0 0 0 0 % S
% Thr: 0 0 0 19 10 0 0 64 0 10 10 10 0 0 10 % T
% Val: 0 64 0 0 0 10 0 10 0 10 0 0 0 64 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _