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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R3C
All Species:
31.21
Human Site:
Y120
Identified Species:
76.3
UniProt:
Q969Q6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969Q6
NP_060387.2
453
53316
Y120
G
E
E
A
M
I
N
Y
E
N
F
L
K
V
G
Chimpanzee
Pan troglodytes
XP_001137008
422
49542
F106
A
G
A
K
C
K
Q
F
F
T
A
K
V
F
A
Rhesus Macaque
Macaca mulatta
XP_001084437
453
53335
Y120
G
E
E
A
M
I
N
Y
E
N
F
L
K
V
G
Dog
Lupus familis
XP_537411
453
53541
Y120
G
E
E
A
M
I
N
Y
E
N
F
L
K
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JK24
453
53388
Y120
G
E
E
A
M
I
N
Y
E
N
F
L
K
V
G
Rat
Rattus norvegicus
Q6AXZ3
453
53360
Y120
G
E
E
A
M
I
N
Y
E
N
F
L
K
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512049
446
52354
Y113
G
E
E
A
M
I
N
Y
E
N
F
L
K
V
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083289
344
40812
E28
E
Q
E
M
K
E
E
E
M
S
L
F
T
N
Y
Zebra Danio
Brachydanio rerio
Q803V3
457
53314
Y123
G
D
E
A
M
I
S
Y
E
S
F
L
K
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397305
444
51808
Y114
G
E
E
Q
L
I
N
Y
E
D
F
K
K
V
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
99.1
98
N.A.
98.2
97.7
N.A.
91.1
N.A.
65.1
85.5
N.A.
N.A.
69.3
N.A.
N.A.
Protein Similarity:
100
93.1
99.1
98.4
N.A.
99.1
99.1
N.A.
94.6
N.A.
70.4
93
N.A.
N.A.
82.7
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
100
N.A.
6.6
80
N.A.
N.A.
73.3
N.A.
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
100
N.A.
20
100
N.A.
N.A.
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
70
0
0
0
0
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
10
70
90
0
0
10
10
10
80
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
10
0
80
10
0
10
0
% F
% Gly:
80
10
0
0
0
0
0
0
0
0
0
0
0
0
80
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
80
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
10
0
0
0
0
0
20
80
0
0
% K
% Leu:
0
0
0
0
10
0
0
0
0
0
10
70
0
0
0
% L
% Met:
0
0
0
10
70
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
70
0
0
60
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
10
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
0
0
20
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
10
80
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _