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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OSBP2
All Species:
5.15
Human Site:
S143
Identified Species:
10.3
UniProt:
Q969R2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969R2
NP_110385.1
916
101266
S143
F
L
R
P
E
S
G
S
L
P
A
L
K
P
L
Chimpanzee
Pan troglodytes
XP_525565
919
102302
S147
F
L
R
L
E
S
G
S
L
P
A
L
K
P
L
Rhesus Macaque
Macaca mulatta
XP_001090190
805
89207
V50
S
G
A
A
S
G
T
V
V
A
A
A
A
G
G
Dog
Lupus familis
XP_534736
872
96557
R117
G
R
Q
E
L
G
S
R
A
G
A
G
P
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5QNQ6
908
101335
V139
S
T
V
G
S
L
P
V
T
K
P
E
S
K
L
Rat
Rattus norvegicus
Q8K4M9
950
107747
S162
A
E
V
S
A
L
L
S
R
P
N
P
P
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505999
738
84284
Chicken
Gallus gallus
XP_415293
788
88247
P33
A
C
H
E
L
P
G
P
G
R
R
A
M
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477271
784
89306
I28
L
L
K
W
T
N
Y
I
K
G
Y
Q
R
R
W
Honey Bee
Apis mellifera
XP_392480
836
95642
Q80
S
K
T
Q
H
G
T
Q
E
M
K
G
W
L
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790853
566
64483
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12451
1283
145778
K472
D
N
L
T
E
S
G
K
R
F
V
S
K
M
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
55.7
82.7
N.A.
82.7
26.6
N.A.
52.2
64.7
N.A.
N.A.
N.A.
31.9
44.2
N.A.
36
Protein Similarity:
100
93.4
68
87.5
N.A.
87.9
41.5
N.A.
64
73.6
N.A.
N.A.
N.A.
49.1
59.9
N.A.
46.1
P-Site Identity:
100
93.3
6.6
6.6
N.A.
6.6
13.3
N.A.
0
6.6
N.A.
N.A.
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
93.3
13.3
13.3
N.A.
6.6
20
N.A.
0
6.6
N.A.
N.A.
N.A.
26.6
0
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
9
9
0
0
0
9
9
34
17
9
0
9
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% D
% Glu:
0
9
0
17
25
0
0
0
9
0
0
9
0
0
0
% E
% Phe:
17
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% F
% Gly:
9
9
0
9
0
25
34
0
9
17
0
17
0
9
9
% G
% His:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% I
% Lys:
0
9
9
0
0
0
0
9
9
9
9
0
25
9
0
% K
% Leu:
9
25
9
9
17
17
9
0
17
0
0
17
0
9
25
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
9
9
0
% M
% Asn:
0
9
0
0
0
9
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
9
0
9
9
9
0
25
9
9
17
17
0
% P
% Gln:
0
0
9
9
0
0
0
9
0
0
0
9
0
0
0
% Q
% Arg:
0
9
17
0
0
0
0
9
17
9
9
0
9
9
0
% R
% Ser:
25
0
0
9
17
25
9
25
0
0
0
9
9
9
9
% S
% Thr:
0
9
9
9
9
0
17
0
9
0
0
0
0
0
0
% T
% Val:
0
0
17
0
0
0
0
17
9
0
9
0
0
0
9
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
9
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _