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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OSBP2
All Species:
6.36
Human Site:
S333
Identified Species:
12.73
UniProt:
Q969R2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969R2
NP_110385.1
916
101266
S333
H
G
A
A
L
Q
R
S
L
T
E
L
D
G
L
Chimpanzee
Pan troglodytes
XP_525565
919
102302
S337
H
G
A
A
L
Q
R
S
L
T
E
L
D
G
L
Rhesus Macaque
Macaca mulatta
XP_001090190
805
89207
S238
T
A
L
Q
R
S
L
S
E
L
E
S
L
K
L
Dog
Lupus familis
XP_534736
872
96557
A305
D
D
E
T
T
S
P
A
D
K
S
E
L
H
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q5QNQ6
908
101335
R330
K
H
G
A
A
L
Q
R
S
L
N
E
L
D
S
Rat
Rattus norvegicus
Q8K4M9
950
107747
V353
T
D
D
E
E
E
D
V
A
S
A
M
D
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505999
738
84284
L170
G
T
A
L
Q
R
S
L
S
E
L
E
S
L
K
Chicken
Gallus gallus
XP_415293
788
88247
L221
S
L
S
E
L
E
N
L
K
L
P
A
E
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477271
784
89306
K216
A
Q
G
H
K
W
S
K
M
L
H
H
E
R
E
Honey Bee
Apis mellifera
XP_392480
836
95642
E268
A
M
V
N
A
S
N
E
Y
L
Q
L
A
Q
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790853
566
64483
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12451
1283
145778
T702
K
L
L
E
S
H
A
T
A
G
N
K
E
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
55.7
82.7
N.A.
82.7
26.6
N.A.
52.2
64.7
N.A.
N.A.
N.A.
31.9
44.2
N.A.
36
Protein Similarity:
100
93.4
68
87.5
N.A.
87.9
41.5
N.A.
64
73.6
N.A.
N.A.
N.A.
49.1
59.9
N.A.
46.1
P-Site Identity:
100
100
20
0
N.A.
6.6
6.6
N.A.
6.6
6.6
N.A.
N.A.
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
20
6.6
N.A.
13.3
26.6
N.A.
13.3
26.6
N.A.
N.A.
N.A.
13.3
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
25
25
17
0
9
9
17
0
9
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
17
9
0
0
0
9
0
9
0
0
0
25
9
0
% D
% Glu:
0
0
9
25
9
17
0
9
9
9
25
25
25
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
17
17
0
0
0
0
0
0
9
0
0
0
17
9
% G
% His:
17
9
0
9
0
9
0
0
0
0
9
9
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
17
0
0
0
9
0
0
9
9
9
0
9
0
9
17
% K
% Leu:
0
17
17
9
25
9
9
17
17
42
9
25
25
17
34
% L
% Met:
0
9
0
0
0
0
0
0
9
0
0
9
0
0
0
% M
% Asn:
0
0
0
9
0
0
17
0
0
0
17
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% P
% Gln:
0
9
0
9
9
17
9
0
0
0
9
0
0
9
9
% Q
% Arg:
0
0
0
0
9
9
17
9
0
0
0
0
0
9
0
% R
% Ser:
9
0
9
0
9
25
17
25
17
9
9
9
9
17
9
% S
% Thr:
17
9
0
9
9
0
0
9
0
17
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _