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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OSBP2
All Species:
0.91
Human Site:
S428
Identified Species:
1.82
UniProt:
Q969R2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969R2
NP_110385.1
916
101266
S428
P
G
R
P
A
N
P
S
K
S
F
I
E
G
S
Chimpanzee
Pan troglodytes
XP_525565
919
102302
P431
A
P
G
R
P
T
N
P
S
K
S
F
I
E
G
Rhesus Macaque
Macaca mulatta
XP_001090190
805
89207
T330
A
T
V
L
P
A
N
T
P
G
S
V
G
S
G
Dog
Lupus familis
XP_534736
872
96557
L397
S
R
K
W
Q
R
A
L
Q
Y
E
R
D
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5QNQ6
908
101335
S425
T
P
G
G
P
A
S
S
S
K
S
F
S
E
G
Rat
Rattus norvegicus
Q8K4M9
950
107747
H454
L
E
T
L
A
T
E
H
H
E
L
E
R
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505999
738
84284
N262
G
A
T
V
L
P
A
N
T
P
G
S
A
G
S
Chicken
Gallus gallus
XP_415293
788
88247
G313
G
S
A
G
T
T
K
G
Q
C
L
S
A
K
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477271
784
89306
R309
I
L
K
M
H
K
R
R
S
S
S
E
D
Q
V
Honey Bee
Apis mellifera
XP_392480
836
95642
P360
T
L
S
I
P
G
V
P
T
N
N
S
R
D
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790853
566
64483
V91
E
V
E
R
Q
R
W
V
T
A
L
E
L
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12451
1283
145778
K803
K
I
E
S
N
V
E
K
T
S
Q
K
F
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
55.7
82.7
N.A.
82.7
26.6
N.A.
52.2
64.7
N.A.
N.A.
N.A.
31.9
44.2
N.A.
36
Protein Similarity:
100
93.4
68
87.5
N.A.
87.9
41.5
N.A.
64
73.6
N.A.
N.A.
N.A.
49.1
59.9
N.A.
46.1
P-Site Identity:
100
0
0
0
N.A.
6.6
6.6
N.A.
13.3
0
N.A.
N.A.
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
0
13.3
20
N.A.
6.6
6.6
N.A.
20
6.6
N.A.
N.A.
N.A.
20
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
9
0
17
17
17
0
0
9
0
0
17
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
17
9
0
% D
% Glu:
9
9
17
0
0
0
17
0
0
9
9
25
9
25
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
17
9
0
0
% F
% Gly:
17
9
17
17
0
9
0
9
0
9
9
0
9
17
34
% G
% His:
0
0
0
0
9
0
0
9
9
0
0
0
0
0
0
% H
% Ile:
9
9
0
9
0
0
0
0
0
0
0
9
9
0
0
% I
% Lys:
9
0
17
0
0
9
9
9
9
17
0
9
0
9
17
% K
% Leu:
9
17
0
17
9
0
0
9
0
0
25
0
9
0
9
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
9
17
9
0
9
9
0
0
0
0
% N
% Pro:
9
17
0
9
34
9
9
17
9
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
17
0
0
0
17
0
9
0
0
17
0
% Q
% Arg:
0
9
9
17
0
17
9
9
0
0
0
9
17
0
17
% R
% Ser:
9
9
9
9
0
0
9
17
25
25
34
25
9
17
17
% S
% Thr:
17
9
17
0
9
25
0
9
34
0
0
0
0
0
0
% T
% Val:
0
9
9
9
0
9
9
9
0
0
0
9
0
0
9
% V
% Trp:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _