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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OSBP2
All Species:
10.61
Human Site:
T246
Identified Species:
21.21
UniProt:
Q969R2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969R2
NP_110385.1
916
101266
T246
D
S
C
G
I
L
L
T
S
G
A
R
S
Y
H
Chimpanzee
Pan troglodytes
XP_525565
919
102302
T250
D
S
C
G
I
L
L
T
S
G
A
R
S
Y
H
Rhesus Macaque
Macaca mulatta
XP_001090190
805
89207
N151
S
C
N
F
I
I
S
N
G
G
A
Q
T
Y
H
Dog
Lupus familis
XP_534736
872
96557
L218
F
V
L
S
N
G
L
L
S
Y
Y
R
N
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5QNQ6
908
101335
C243
D
S
C
G
I
L
L
C
N
G
A
R
T
Y
H
Rat
Rattus norvegicus
Q8K4M9
950
107747
Y266
E
H
G
V
L
S
W
Y
R
K
Q
P
D
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505999
738
84284
S83
D
S
C
N
F
I
I
S
N
G
G
A
Q
T
Y
Chicken
Gallus gallus
XP_415293
788
88247
Y134
L
S
N
G
G
R
T
Y
H
L
K
A
S
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477271
784
89306
S129
E
T
A
H
V
V
P
S
Q
E
I
S
S
V
V
Honey Bee
Apis mellifera
XP_392480
836
95642
E181
A
I
Q
A
M
E
S
E
E
E
E
E
E
F
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790853
566
64483
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12451
1283
145778
P615
I
E
Q
E
E
P
S
P
E
V
W
L
T
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
55.7
82.7
N.A.
82.7
26.6
N.A.
52.2
64.7
N.A.
N.A.
N.A.
31.9
44.2
N.A.
36
Protein Similarity:
100
93.4
68
87.5
N.A.
87.9
41.5
N.A.
64
73.6
N.A.
N.A.
N.A.
49.1
59.9
N.A.
46.1
P-Site Identity:
100
100
33.3
20
N.A.
80
0
N.A.
26.6
20
N.A.
N.A.
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
53.3
26.6
N.A.
93.3
13.3
N.A.
60
20
N.A.
N.A.
N.A.
40
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
9
0
0
0
0
0
0
34
17
0
9
0
% A
% Cys:
0
9
34
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
34
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
17
9
0
9
9
9
0
9
17
17
9
9
9
0
9
% E
% Phe:
9
0
0
9
9
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
9
34
9
9
0
0
9
42
9
0
0
0
9
% G
% His:
0
9
0
9
0
0
0
0
9
0
0
0
0
0
34
% H
% Ile:
9
9
0
0
34
17
9
0
0
0
9
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
9
% K
% Leu:
9
0
9
0
9
25
34
9
0
9
0
9
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
17
9
9
0
0
9
17
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
9
9
9
0
0
0
9
0
0
0
% P
% Gln:
0
0
17
0
0
0
0
0
9
0
9
9
9
9
9
% Q
% Arg:
0
0
0
0
0
9
0
0
9
0
0
34
0
0
0
% R
% Ser:
9
42
0
9
0
9
25
17
25
0
0
9
34
9
0
% S
% Thr:
0
9
0
0
0
0
9
17
0
0
0
0
25
9
0
% T
% Val:
0
9
0
9
9
9
0
0
0
9
0
0
0
9
17
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
17
0
9
9
0
0
34
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _