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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OSBP2
All Species:
10.91
Human Site:
Y722
Identified Species:
21.82
UniProt:
Q969R2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969R2
NP_110385.1
916
101266
Y722
L
K
F
L
P
Y
S
Y
F
S
K
E
A
A
R
Chimpanzee
Pan troglodytes
XP_525565
919
102302
Y725
L
K
F
L
P
Y
S
Y
F
S
K
E
A
A
R
Rhesus Macaque
Macaca mulatta
XP_001090190
805
89207
K624
F
S
R
D
V
A
R
K
V
T
G
E
V
T
D
Dog
Lupus familis
XP_534736
872
96557
T691
V
W
R
K
S
T
S
T
V
H
N
I
I
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5QNQ6
908
101335
Y719
L
K
F
V
P
Y
S
Y
F
S
K
E
A
A
R
Rat
Rattus norvegicus
Q8K4M9
950
107747
L748
L
N
F
K
P
C
G
L
F
G
K
E
L
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505999
738
84284
R556
Y
F
S
R
D
V
A
R
K
V
T
G
E
V
M
Chicken
Gallus gallus
XP_415293
788
88247
V607
S
R
D
V
P
R
K
V
T
G
V
V
S
D
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477271
784
89306
R603
I
P
Y
S
Y
F
S
R
D
V
Q
R
S
V
K
Honey Bee
Apis mellifera
XP_392480
836
95642
S654
Y
T
P
Y
S
Y
F
S
R
D
S
Q
R
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790853
566
64483
Y385
R
L
T
E
D
M
F
Y
S
D
L
L
S
M
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12451
1283
145778
R1097
C
K
L
Y
F
K
A
R
G
W
R
S
S
G
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
55.7
82.7
N.A.
82.7
26.6
N.A.
52.2
64.7
N.A.
N.A.
N.A.
31.9
44.2
N.A.
36
Protein Similarity:
100
93.4
68
87.5
N.A.
87.9
41.5
N.A.
64
73.6
N.A.
N.A.
N.A.
49.1
59.9
N.A.
46.1
P-Site Identity:
100
100
6.6
6.6
N.A.
93.3
40
N.A.
0
6.6
N.A.
N.A.
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
13.3
13.3
N.A.
100
46.6
N.A.
6.6
26.6
N.A.
N.A.
N.A.
46.6
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
17
0
0
0
0
0
25
25
25
% A
% Cys:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
17
0
0
0
9
17
0
0
0
9
9
% D
% Glu:
0
0
0
9
0
0
0
0
0
0
0
42
9
0
0
% E
% Phe:
9
9
34
0
9
9
17
0
34
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
9
17
9
9
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% I
% Lys:
0
34
0
17
0
9
9
9
9
0
34
0
0
9
17
% K
% Leu:
34
9
9
17
0
0
0
9
0
0
9
9
9
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
9
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
9
9
0
42
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% Q
% Arg:
9
9
17
9
0
9
9
25
9
0
9
9
9
0
25
% R
% Ser:
9
9
9
9
17
0
42
9
9
25
9
9
34
0
0
% S
% Thr:
0
9
9
0
0
9
0
9
9
9
9
0
0
9
0
% T
% Val:
9
0
0
17
9
9
0
9
17
17
9
9
9
25
9
% V
% Trp:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
17
0
9
17
9
34
0
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _