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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: L3MBTL2 All Species: 36.36
Human Site: S227 Identified Species: 72.73
UniProt: Q969R5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969R5 NP_113676.2 705 79110 S227 N S D A V L P S R V Y W I A S
Chimpanzee Pan troglodytes XP_001168767 705 79052 S227 N S D A V L P S R V Y W I A S
Rhesus Macaque Macaca mulatta XP_001103491 705 78955 S227 N S D A V L P S R V Y W I A S
Dog Lupus familis XP_538356 707 79354 S229 N S D A V L P S R V Y W I A S
Cat Felis silvestris
Mouse Mus musculus P59178 703 78936 S227 N S D A V L P S R V Y W I A T
Rat Rattus norvegicus Q3MIF2 703 78948 S227 N S D A V L P S R V Y W I A T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518844 715 80288 S232 N N D A V L P S R V Y W I A S
Chicken Gallus gallus NP_001006238 723 81164 S243 N S D A V L P S R V Y W I A S
Frog Xenopus laevis Q32N90 621 69793 C182 V I A A P V T C F R H A P M G
Zebra Danio Brachydanio rerio NP_956326 805 90717 S301 N T H T A L P S K V Y W I A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VK33 1220 133648 T591 E V I Q P G Q T P T S F W V A
Honey Bee Apis mellifera XP_397193 889 100688 P275 D E V C E A F P D S F W V A T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.5 95.7 N.A. 91.2 91.7 N.A. 83.5 77.8 51.4 48.3 N.A. 28.4 31.8 N.A. N.A.
Protein Similarity: 100 99.8 99 97.4 N.A. 95 94.7 N.A. 90.6 86.4 65.6 62.3 N.A. 40.4 46.1 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 100 6.6 60 N.A. 0 13.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 20 80 N.A. 20 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 75 9 9 0 0 0 0 0 9 0 84 9 % A
% Cys: 0 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 9 0 67 0 0 0 0 0 9 0 0 0 0 0 0 % D
% Glu: 9 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 9 0 9 9 0 0 0 % F
% Gly: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 9 % G
% His: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 9 9 0 0 0 0 0 0 0 0 0 75 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 75 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 75 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 17 0 75 9 9 0 0 0 9 0 0 % P
% Gln: 0 0 0 9 0 0 9 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 67 9 0 0 0 0 0 % R
% Ser: 0 59 0 0 0 0 0 75 0 9 9 0 0 0 50 % S
% Thr: 0 9 0 9 0 0 9 9 0 9 0 0 0 0 34 % T
% Val: 9 9 9 0 67 9 0 0 0 75 0 0 9 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 84 9 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 75 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _