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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC35B4 All Species: 18.18
Human Site: S146 Identified Species: 36.36
UniProt: Q969S0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969S0 NP_116215.1 331 37424 S146 A K Q V T S Q S S L S E N D G
Chimpanzee Pan troglodytes XP_001139604 231 25720 E51 A V E G F L F E A D L G R K P
Rhesus Macaque Macaca mulatta XP_001100494 331 37376 S146 A K Q V T S Q S S L S E N D G
Dog Lupus familis XP_539368 330 37252 S146 A K Q V T S E S S S S E N D G
Cat Felis silvestris
Mouse Mus musculus Q8CIA5 331 37498 T146 A K Q V T V Q T G L S D K D G
Rat Rattus norvegicus Q6V7K3 322 35798 Y136 V T L L K K K Y P L A K Y L C
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q8AWB6 325 36035 Y139 V T V L R K K Y P L A K Y L C
Frog Xenopus laevis Q6GQ70 320 35333 Y134 V T L L R K K Y P L T K Y L C
Zebra Danio Brachydanio rerio Q7ZW46 331 37202 K146 A K Q V N V E K G G T E E D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W429 352 39476 T150 S G D V K D N T H H S L K V D
Honey Bee Apis mellifera XP_001120356 334 38039 Q145 G K E I K S L Q P K N I E Q V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40004 342 39248 D153 D A D F R Y Q D L K L Q A W K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 69.4 98.7 94.8 N.A. 90.9 26.8 N.A. N.A. 25.3 25.6 73.1 N.A. 51.9 52.6 N.A. N.A.
Protein Similarity: 100 69.7 99.6 98.4 N.A. 95.4 44.4 N.A. N.A. 43.8 42.5 83.3 N.A. 70.7 73.6 N.A. N.A.
P-Site Identity: 100 6.6 100 86.6 N.A. 66.6 6.6 N.A. N.A. 6.6 6.6 46.6 N.A. 13.3 13.3 N.A. N.A.
P-Site Similarity: 100 20 100 93.3 N.A. 80 33.3 N.A. N.A. 33.3 33.3 60 N.A. 26.6 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 9 0 0 0 0 0 0 9 0 17 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % C
% Asp: 9 0 17 0 0 9 0 9 0 9 0 9 0 42 9 % D
% Glu: 0 0 17 0 0 0 17 9 0 0 0 34 17 0 0 % E
% Phe: 0 0 0 9 9 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 9 9 0 9 0 0 0 0 17 9 0 9 0 0 42 % G
% His: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 0 0 0 0 9 0 0 0 % I
% Lys: 0 50 0 0 25 25 25 9 0 17 0 25 17 9 9 % K
% Leu: 0 0 17 25 0 9 9 0 9 50 17 9 0 25 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 9 0 0 0 9 0 25 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 34 0 0 0 0 0 9 % P
% Gln: 0 0 42 0 0 0 34 9 0 0 0 9 0 9 0 % Q
% Arg: 0 0 0 0 25 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 9 0 0 0 0 34 0 25 25 9 42 0 0 0 0 % S
% Thr: 0 25 0 0 34 0 0 17 0 0 17 0 0 0 0 % T
% Val: 25 9 9 50 0 17 0 0 0 0 0 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 0 0 0 9 0 25 0 0 0 0 25 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _