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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDAC10
All Species:
22.42
Human Site:
S637
Identified Species:
41.11
UniProt:
Q969S8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969S8
NP_001152758.1
669
71445
S637
P
P
S
L
G
P
S
S
V
A
S
P
E
D
V
Chimpanzee
Pan troglodytes
XP_515218
669
71461
S637
P
P
S
L
G
P
S
S
V
A
S
P
E
D
V
Rhesus Macaque
Macaca mulatta
XP_001112365
671
71733
S639
P
P
S
L
G
P
S
S
V
A
S
P
E
D
V
Dog
Lupus familis
XP_848669
830
88564
S636
P
P
S
L
G
P
F
S
T
A
P
P
E
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6P3E7
666
72091
S635
P
P
S
L
G
P
F
S
K
A
T
P
E
E
I
Rat
Rattus norvegicus
Q569C4
588
63939
S557
P
P
S
L
G
P
F
S
M
A
S
P
E
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509232
334
36373
G315
W
T
C
L
R
Q
E
G
T
R
L
E
T
A
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089352
683
76715
R638
E
K
H
F
G
P
H
R
A
P
S
L
E
N
I
Zebra Danio
Brachydanio rerio
NP_956069
676
74999
R644
I
S
P
L
G
P
L
R
A
P
K
P
E
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727843
1138
125987
E986
K
E
A
L
E
Q
S
E
M
F
A
V
Y
P
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20296
955
106730
T854
H
A
V
V
P
L
A
T
C
P
H
L
K
E
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LRK8
682
76616
H661
K
K
N
M
E
R
S
H
K
K
F
I
K
D
M
Baker's Yeast
Sacchar. cerevisiae
P53973
706
80051
N682
C
D
T
D
G
L
N
N
I
I
E
E
R
F
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.2
63.8
N.A.
75.4
66.3
N.A.
33
N.A.
48.6
45.1
N.A.
26.1
N.A.
23
N.A.
Protein Similarity:
100
99.4
97.1
69.8
N.A.
83.2
72.8
N.A.
40.2
N.A.
65
61.3
N.A.
36.7
N.A.
39.2
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
66.6
73.3
N.A.
6.6
N.A.
26.6
46.6
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
86.6
93.3
N.A.
6.6
N.A.
40
46.6
N.A.
40
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.1
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.7
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
8
0
16
47
8
0
0
8
0
% A
% Cys:
8
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
0
0
0
0
0
0
0
0
47
0
% D
% Glu:
8
8
0
0
16
0
8
8
0
0
8
16
62
24
8
% E
% Phe:
0
0
0
8
0
0
24
0
0
8
8
0
0
8
0
% F
% Gly:
0
0
0
0
70
0
0
8
0
0
0
0
0
0
8
% G
% His:
8
0
8
0
0
0
8
8
0
0
8
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
8
8
0
8
0
0
24
% I
% Lys:
16
16
0
0
0
0
0
0
16
8
8
0
16
0
0
% K
% Leu:
0
0
0
70
0
16
8
0
0
0
8
16
0
0
8
% L
% Met:
0
0
0
8
0
0
0
0
16
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
0
8
8
0
0
0
0
0
8
0
% N
% Pro:
47
47
8
0
8
62
0
0
0
24
8
54
0
8
0
% P
% Gln:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
8
0
16
0
8
0
0
8
0
0
% R
% Ser:
0
8
47
0
0
0
39
47
0
0
39
0
0
0
0
% S
% Thr:
0
8
8
0
0
0
0
8
16
0
8
0
8
0
8
% T
% Val:
0
0
8
8
0
0
0
0
24
0
0
8
0
0
39
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _