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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NT5C3L All Species: 39.7
Human Site: Y260 Identified Species: 79.39
UniProt: Q969T7 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969T7 NP_443167.3 292 33528 Y260 R E R Y M D S Y D I V L E K D
Chimpanzee Pan troglodytes XP_001167609 292 33510 Y260 R E R Y M D S Y D I V L E K D
Rhesus Macaque Macaca mulatta XP_001107648 336 37930 Y315 L E K Y M N S Y D I V L V Q D
Dog Lupus familis XP_548097 300 34563 Y268 R E R Y M D S Y D I V L E K D
Cat Felis silvestris
Mouse Mus musculus Q3UFY7 292 33560 Y260 R E R Y M D S Y D I V L E K D
Rat Rattus norvegicus Q6AYP7 292 33670 Y260 R E R Y M D S Y D I V L E K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506646 336 37870 Y315 L E K Y K D L Y D I V L V K E
Chicken Gallus gallus Q5ZKF6 289 33090 Y265 R G R Y L D A Y D I V L E S D
Frog Xenopus laevis Q7ZWS2 290 33482 Y266 T E Q F L Q S Y D I V L L R D
Zebra Danio Brachydanio rerio Q7SYN4 286 32918 Y265 L E K Y M D S Y N I V L A R D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09315 376 42128 Y352 L Q H Y E E V Y D I V L I H D
Sea Urchin Strong. purpuratus XP_781890 284 31941 F263 L E S Y K D S F D I V L I S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 49.1 90.6 N.A. 89.7 90 N.A. 49.1 63.7 60.6 58.9 N.A. N.A. N.A. 29.2 41.4
Protein Similarity: 100 100 66.9 94.6 N.A. 95.5 95.2 N.A. 67.8 81.5 79.1 79.1 N.A. N.A. N.A. 46.8 60.2
P-Site Identity: 100 100 66.6 100 N.A. 100 100 N.A. 60 73.3 53.3 66.6 N.A. N.A. N.A. 46.6 60
P-Site Similarity: 100 100 86.6 100 N.A. 100 100 N.A. 73.3 86.6 80 86.6 N.A. N.A. N.A. 60 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 0 0 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 75 0 0 92 0 0 0 0 0 92 % D
% Glu: 0 84 0 0 9 9 0 0 0 0 0 0 50 0 9 % E
% Phe: 0 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 100 0 0 17 0 0 % I
% Lys: 0 0 25 0 17 0 0 0 0 0 0 0 0 50 0 % K
% Leu: 42 0 0 0 17 0 9 0 0 0 0 100 9 0 0 % L
% Met: 0 0 0 0 59 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 9 0 0 9 0 0 0 0 0 0 0 9 0 % Q
% Arg: 50 0 50 0 0 0 0 0 0 0 0 0 0 17 0 % R
% Ser: 0 0 9 0 0 0 75 0 0 0 0 0 0 17 0 % S
% Thr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 9 0 0 0 100 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 92 0 0 0 92 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _