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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NCLN
All Species:
30.3
Human Site:
S404
Identified Species:
51.28
UniProt:
Q969V3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969V3
NP_064555.2
563
62974
S404
S
S
I
M
D
V
R
S
R
V
D
S
K
T
L
Chimpanzee
Pan troglodytes
XP_524050
707
77610
S541
S
S
I
M
D
V
R
S
R
V
D
S
K
T
L
Rhesus Macaque
Macaca mulatta
XP_001100206
667
74077
S404
S
S
I
M
D
V
R
S
R
V
D
S
K
T
L
Dog
Lupus familis
XP_542180
892
96824
S733
S
S
I
M
D
V
R
S
R
V
D
S
K
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCM8
563
62890
S404
S
S
I
M
D
V
R
S
R
V
D
S
K
T
L
Rat
Rattus norvegicus
Q5XIA1
563
62974
S404
S
S
I
M
D
V
R
S
R
V
D
S
K
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521328
545
60941
D390
S
L
L
N
S
H
R
D
G
L
R
N
S
I
M
Chicken
Gallus gallus
Q5ZJH2
562
62405
S403
N
S
I
M
D
R
R
S
Q
V
D
T
K
A
L
Frog
Xenopus laevis
NP_001085433
560
63363
W401
N
S
I
L
D
L
R
W
K
V
D
T
Q
V
L
Zebra Danio
Brachydanio rerio
Q6NZ07
572
63970
P412
A
G
E
A
T
T
G
P
H
V
D
L
G
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609378
561
63122
S393
S
S
V
K
S
P
R
S
P
I
R
T
T
I
F
Honey Bee
Apis mellifera
XP_394739
540
60260
D390
S
T
L
K
S
H
E
D
P
I
R
T
T
I
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797082
246
27954
D97
H
K
R
I
N
L
G
D
D
W
L
A
W
E
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001147070
552
60275
T391
S
T
G
G
L
H
D
T
R
E
S
T
D
V
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
82.6
60
N.A.
93.4
93
N.A.
84
78.5
81.1
74.1
N.A.
35.5
42
N.A.
25.5
Protein Similarity:
100
79.4
83.2
61.5
N.A.
96.8
96.4
N.A.
91.1
87.5
90.4
86
N.A.
55.7
61.6
N.A.
33.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
66.6
46.6
20
N.A.
26.6
13.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
40
86.6
86.6
26.6
N.A.
46.6
40
N.A.
26.6
Percent
Protein Identity:
N.A.
34.1
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
53.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
0
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
58
0
8
22
8
0
65
0
8
0
0
% D
% Glu:
0
0
8
0
0
0
8
0
0
8
0
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
8
8
8
0
0
15
0
8
0
0
0
8
0
0
% G
% His:
8
0
0
0
0
22
0
0
8
0
0
0
0
0
8
% H
% Ile:
0
0
58
8
0
0
0
0
0
15
0
0
0
22
0
% I
% Lys:
0
8
0
15
0
0
0
0
8
0
0
0
50
8
0
% K
% Leu:
0
8
15
8
8
15
0
0
0
8
8
8
0
0
72
% L
% Met:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
15
0
0
8
8
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
8
15
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% Q
% Arg:
0
0
8
0
0
8
72
0
50
0
22
0
0
0
0
% R
% Ser:
72
65
0
0
22
0
0
58
0
0
8
43
8
0
0
% S
% Thr:
0
15
0
0
8
8
0
8
0
0
0
36
15
43
0
% T
% Val:
0
0
8
0
0
43
0
0
0
65
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
8
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _