KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NCLN
All Species:
29.7
Human Site:
T460
Identified Species:
50.26
UniProt:
Q969V3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969V3
NP_064555.2
563
62974
T460
D
S
V
M
D
W
L
T
N
Q
P
R
A
A
Q
Chimpanzee
Pan troglodytes
XP_524050
707
77610
T597
D
S
V
M
D
W
L
T
N
Q
P
R
A
A
Q
Rhesus Macaque
Macaca mulatta
XP_001100206
667
74077
P460
M
D
W
L
T
N
Q
P
R
A
A
Q
L
V
D
Dog
Lupus familis
XP_542180
892
96824
T789
D
S
V
M
D
W
L
T
N
Q
P
R
A
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCM8
563
62890
T460
D
S
V
M
D
W
L
T
N
Q
P
R
A
A
Q
Rat
Rattus norvegicus
Q5XIA1
563
62974
T460
D
S
V
M
D
W
L
T
N
Q
P
R
A
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521328
545
60941
Q446
T
E
Q
M
Q
I
Q
Q
E
Q
L
E
S
V
M
Chicken
Gallus gallus
Q5ZJH2
562
62405
E459
R
I
S
D
G
L
A
E
Q
S
A
Q
A
A
Q
Frog
Xenopus laevis
NP_001085433
560
63363
T457
D
A
V
M
H
W
L
T
N
Q
P
R
A
A
Q
Zebra Danio
Brachydanio rerio
Q6NZ07
572
63970
T468
A
S
L
V
D
W
L
T
A
Q
P
R
A
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609378
561
63122
P449
I
K
E
E
N
I
L
P
Y
F
G
V
K
S
I
Honey Bee
Apis mellifera
XP_394739
540
60260
W446
S
K
E
S
L
S
L
W
F
S
Y
L
A
S
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797082
246
27954
T153
N
V
K
I
I
A
E
T
L
A
H
H
I
F
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001147070
552
60275
S447
R
S
W
L
D
L
L
S
R
T
P
R
V
A
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
82.6
60
N.A.
93.4
93
N.A.
84
78.5
81.1
74.1
N.A.
35.5
42
N.A.
25.5
Protein Similarity:
100
79.4
83.2
61.5
N.A.
96.8
96.4
N.A.
91.1
87.5
90.4
86
N.A.
55.7
61.6
N.A.
33.2
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
13.3
20
86.6
73.3
N.A.
6.6
20
N.A.
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
20
26.6
93.3
86.6
N.A.
20
26.6
N.A.
20
Percent
Protein Identity:
N.A.
34.1
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
53.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
40
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
8
8
0
8
15
15
0
65
65
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
43
8
0
8
50
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
8
15
8
0
0
8
8
8
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
8
0
0
0
8
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
8
8
0
0
0
% H
% Ile:
8
8
0
8
8
15
0
0
0
0
0
0
8
0
8
% I
% Lys:
0
15
8
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
8
15
8
15
72
0
8
0
8
8
8
0
0
% L
% Met:
8
0
0
50
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
0
8
8
0
0
43
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
15
0
0
58
0
0
0
8
% P
% Gln:
0
0
8
0
8
0
15
8
8
58
0
15
0
0
65
% Q
% Arg:
15
0
0
0
0
0
0
0
15
0
0
58
0
0
0
% R
% Ser:
8
50
8
8
0
8
0
8
0
15
0
0
8
15
0
% S
% Thr:
8
0
0
0
8
0
0
58
0
8
0
0
0
0
0
% T
% Val:
0
8
43
8
0
0
0
0
0
0
0
8
8
15
0
% V
% Trp:
0
0
15
0
0
50
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _