Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NCLN All Species: 47.88
Human Site: Y259 Identified Species: 81.03
UniProt: Q969V3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969V3 NP_064555.2 563 62974 Y259 A R L F S R L Y T Y K R T H A
Chimpanzee Pan troglodytes XP_524050 707 77610 Y396 A R L F S R L Y T Y K R T H A
Rhesus Macaque Macaca mulatta XP_001100206 667 74077 Y259 A R L F S R L Y T Y K R T H A
Dog Lupus familis XP_542180 892 96824 Y588 A R L F S R L Y T Y K R T H A
Cat Felis silvestris
Mouse Mus musculus Q8VCM8 563 62890 Y259 A R L F S R L Y T Y K R T H A
Rat Rattus norvegicus Q5XIA1 563 62974 Y259 A R L F S R L Y T Y K R T H A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521328 545 60941 Y259 A R L F S R L Y T Y K R T H A
Chicken Gallus gallus Q5ZJH2 562 62405 Y258 A R L F S R L Y T Y R R T H A
Frog Xenopus laevis NP_001085433 560 63363 Y256 A R L F S R L Y T Y K R T H A
Zebra Danio Brachydanio rerio Q6NZ07 572 63970 Y252 A R L F S R L Y S Y K R T H A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609378 561 63122 Y259 E L F S K L H Y T S S M A P K
Honey Bee Apis mellifera XP_394739 540 60260 Y258 A R L F S I L Y S T S R S R P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797082 246 27954
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001147070 552 60275 Y253 A R L F S R L Y S N P K T R G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 82.6 60 N.A. 93.4 93 N.A. 84 78.5 81.1 74.1 N.A. 35.5 42 N.A. 25.5
Protein Similarity: 100 79.4 83.2 61.5 N.A. 96.8 96.4 N.A. 91.1 87.5 90.4 86 N.A. 55.7 61.6 N.A. 33.2
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 100 93.3 N.A. 13.3 53.3 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 13.3 66.6 N.A. 0
Percent
Protein Identity: N.A. 34.1 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 53.4 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 60 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 73.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 86 0 0 0 0 0 0 0 0 0 0 0 8 0 72 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 86 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 72 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 0 0 0 0 0 65 8 0 0 8 % K
% Leu: 0 8 86 0 0 8 86 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 86 0 0 0 79 0 0 0 0 8 79 0 15 0 % R
% Ser: 0 0 0 8 86 0 0 0 22 8 15 0 8 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 72 8 0 0 79 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 93 0 72 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _